Results 41 to 50 of about 60,917 (260)

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Integrative taxonomy supports two new species of Macrobiotus (Tardigrada: Eutardigrada: Macrobiotidae) allowing further discussion on the genus phylogeny

European Journal of Taxonomy
In this study, I describe two new species of Macrobiotus based on morphological data collected through light and scanning electron microscopy. Both species are accompanied by DNA sequences from four commonly used molecular markers (18S rDNA, 28S rDNA ...
Daniel Stec
doaj   +1 more source

Negative impact of freeze–thaw cycles on the survival of tardigrades

Ecological Indicators, 2023
Global warming effects in temperate and polar regions include higher average temperatures and a decrease in snow cover, which together lead to an increase in the number of freeze–thaw cycles (FTC).
Krzysztof Zawierucha, Matteo Vecchi, Nozomu Takeuchi, Masato Ono, Sara Calhim   +4 more
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Using tri-axial accelerometers to identify wild polar bear behaviors

Endangered Species Research, 2017
Tri-axial accelerometers have been used to remotely identify the behaviors of a wide range of taxa. Assigning behaviors to accelerometer data often involves the use of captive animals or surrogate species, as their accelerometer signatures are generally ...
Pagano, AM, Rode, KD, Cutting, A, Owen, MA, Jensen, S, Ware, JV, Robbins, CT, Durner, GM, Atwood, TC, Obbard, ME, Middel, KR, Thiemann, GW, Williams, TM   +12 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Tardigrade distribution in soils of high Arctic habitats

Ecology and Evolution
Tardigrades are omnipresent microfauna with scarce record on their ecology in soils. Here, we investigated soil inhabiting tardigrade communities in five contrasting polar habitats, evaluating their abundance, diversity, species richness, and species ...
Michala Tůmová, Veronika Jílková, Petr Macek, Miloslav Devetter   +3 more
doaj   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Integrative redescription of the Xerobiotus euxinus Pilato, Kiosya, Lisi, Inshina & Biserov, 2011 (Tardigrada: Eutardigrada: Macrobiotidae) population from Ukraine

The European Zoological Journal
Using integrative taxonomy, we redescribe an eutardigrade Xerobiotus euxinus Pilato et al. 2011 based on material from the type locality and additional population from the Black Sea Biosphere Reserve in the south of Ukraine.
A. Polishchuk, P. Kayastha, Y. Kiosya, M. Mioduchowska, M. Gawlak, Ł. Kaczmarek   +5 more
doaj   +1 more source

Water bears and water loss: Tardigrades and anhydrobiosis [PDF]

The Biochemist, 2008
The Phylum Tardigrada consists of about 900 known species of microscopic animals that are often referred to by their endearing popular names, water bears or moss piglets (translated from the German expressions Wasser Bär and Mooschweinchen). The group is considered a sister group to the arthropods, with animals typically less than 0.5 mm in length1. As
openaire   +1 more source