Results 71 to 80 of about 1,624,308 (352)

Bahr Yousef meandering canal management – Hydraulic and morphological assessment

open access: yesWater Science
Bahr Yousef is a meandering earthen canal and is considered one of the most morphologically active semi-natural streams in the west of River Nile region in Egypt.
Basma Samir Radi Awad   +5 more
doaj   +1 more source

Hydrographic measurements in Jökulsárlón lagoon, Iceland [PDF]

open access: yes, 2013
Jökulsárlón lagoon is an enclosed lake bordering the retreating Breidamerkurjökull glacier which flows down from the Vatnajökull ice cap. As the glacier calves most of the ice it releases decays within the lake and the addition of the stored fresh water ...
Björnsson, Helgi   +3 more
core  

Scalable synthesis of ionic liquids: comparison of performances of microstructured and stirred batch reactors [PDF]

open access: yes, 2012
A range of alkylpyridinium bromide ionic liquids have been synthesized in a stirred reactor at multigram scale and characterized by physical methods (viscosity, conductivity, melting point, electrochemical window, and water content).
Chaumat, Hélène   +5 more
core   +3 more sources

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Aquaporin Water Channels and Hydrocephalus

open access: yesPediatric Neurosurgery, 2016
The aquaporins (AQPs) are a family of water-transporting proteins that are broadly expressed in mammalian cells. Two AQPs in the central nervous system, AQP1 and AQP4, might play a role in hydrocephalus and are thus potential drug targets. AQP1 is expressed in the ventricular-facing membrane of choroid plexus epithelial cells, where it facilitates the ...
Alan S, Verkman   +3 more
openaire   +3 more sources

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

The driving factors of water use and its decoupling relationship with economic development—A multi-sectoral perspective in the nine provinces of the Yellow River Basin

open access: yesJournal of Hydrology: Regional Studies
Study region: Yellow River Nine Provinces (China) Study focus: This study analyzes water consumption drivers in agriculture, industry, and domestic sectors using the LMDI method. It explores the relationship between water use and economic development via
Shengqi Jian   +3 more
doaj   +1 more source

A water level relationship between consecutive gauge stations along Solim\~oes/Amazonas main channel: a wavelet approach

open access: yes, 2013
Gauge stations are distributed along the Solim\~oes/Amazonas main channel to monitor water level changes over time. Those measurements help quantify both the water movement and its variability from one gauge station to the next downstream.
Novo, E. M. L.   +3 more
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

The effect of water stage on the infiltration rate for initially dry channels [PDF]

open access: yes, 2007
Several hydrological models that are used for simulating the water flow in rivers and channels are based on the shallow water equations as in Copeland and El-Hanafy, (2006) or Saint Venant equations (El-Hanafy and Copeland, 2007a). Both the shallow water
Copeland, Graham J.M., Elhanafy, Hossam
core  

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