Results 51 to 60 of about 1,621,904 (302)
C57L mice are susceptible and AKR mice are resistant to gallstone formation. We studied in male mice of both strains gallbladder histopathology, cholecystokinin-induced emptying, and concentrating function at 0, 14, 28, and 56 days on a lithogenic diet ...
Karel J. van Erpecum +8 more
doaj +1 more source
Along-the-channel modeling and analysis of PEFCs at low stoichiometry: Development of a 1+2D model [PDF]
Water management remains a key challenge in polymer-electrolyte fuel cells. In this work, a pseudo 3-D (1+2D) model is developed to account better for changes of water management along the channel, as well as verify the possibilities of using ...
Borup, RL +5 more
core
secCl is a cys-loop ion channel necessary for the chloride conductance that mediates hormone-induced fluid secretion in Drosophila [PDF]
Organisms use circulating diuretic hormones to control water balance (osmolarity), thereby avoiding dehydration and managing excretion of waste products.
Dent, J. +6 more
core +2 more sources
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Increased Permeability of the Aquaporin SoPIP2;1 by Mercury and Mutations in Loop A
Aquaporins (AQPs) also referred to as Major intrinsic proteins, regulate permeability of biological membranes for water and other uncharged small polar molecules.
Andreas Kirscht +3 more
doaj +1 more source
Gravity currents in rotating, wedge-shaped, adverse channels [PDF]
Results are presented from a series of parametric experimental and analytical studies of the behaviour of dense gravity currents along rotating, up-sloping, wedge-shaped channels.
Cuthbertson, A. J. S. +3 more
core +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
The present study was initiated with the objective of simulating and predicting the effect of future development on the groundwater flow and levels. This supports applications for future planning and wise management of water resources.
Mohamed M. Sobeih +3 more
doaj +1 more source
Herbicidan control of water hyacinth at Ere, Ogun State: implications for fish production [PDF]
A brief account is given of a pilot demonstration of the chemical control of water hyacinth (Eichhornia crassipes) at Ere (a channel) in Nigeria using the herbicide glyphosphate.
Adekoya, B.B. +11 more
core

