Results 51 to 60 of about 1,621,904 (302)

Gallbladder histopathology during murine gallstone formation: relation to motility and concentrating function

open access: yesJournal of Lipid Research, 2006
C57L mice are susceptible and AKR mice are resistant to gallstone formation. We studied in male mice of both strains gallbladder histopathology, cholecystokinin-induced emptying, and concentrating function at 0, 14, 28, and 56 days on a lithogenic diet ...
Karel J. van Erpecum   +8 more
doaj   +1 more source

Along-the-channel modeling and analysis of PEFCs at low stoichiometry: Development of a 1+2D model [PDF]

open access: yes, 2019
Water management remains a key challenge in polymer-electrolyte fuel cells. In this work, a pseudo 3-D (1+2D) model is developed to account better for changes of water management along the channel, as well as verify the possibilities of using ...
Borup, RL   +5 more
core  

secCl is a cys-loop ion channel necessary for the chloride conductance that mediates hormone-induced fluid secretion in Drosophila [PDF]

open access: yes, 2019
Organisms use circulating diuretic hormones to control water balance (osmolarity), thereby avoiding dehydration and managing excretion of waste products.
Dent, J.   +6 more
core   +2 more sources

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Increased Permeability of the Aquaporin SoPIP2;1 by Mercury and Mutations in Loop A

open access: yesFrontiers in Plant Science, 2016
Aquaporins (AQPs) also referred to as Major intrinsic proteins, regulate permeability of biological membranes for water and other uncharged small polar molecules.
Andreas Kirscht   +3 more
doaj   +1 more source

Gravity currents in rotating, wedge-shaped, adverse channels [PDF]

open access: yes, 2013
Results are presented from a series of parametric experimental and analytical studies of the behaviour of dense gravity currents along rotating, up-sloping, wedge-shaped channels.
Cuthbertson, A. J. S.   +3 more
core   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Management of water resources to control groundwater levels in the southern area of the western Nile delta, Egypt

open access: yesWater Science, 2017
The present study was initiated with the objective of simulating and predicting the effect of future development on the groundwater flow and levels. This supports applications for future planning and wise management of water resources.
Mohamed M. Sobeih   +3 more
doaj   +1 more source

Herbicidan control of water hyacinth at Ere, Ogun State: implications for fish production [PDF]

open access: yes, 1993
A brief account is given of a pilot demonstration of the chemical control of water hyacinth (Eichhornia crassipes) at Ere (a channel) in Nigeria using the herbicide glyphosphate.
Adekoya, B.B.   +11 more
core  

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