Results 81 to 90 of about 463,394 (315)

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

A multifunctional synergy development evaluation model of the impact of the cascade reservoir construction sequence on basins

Ecological Indicators
Considering the mass reservoirs construction, it is important to study the cascade reservoir construction sequence, which directly affects the water and sediment resource allocation, ecological environment restoration, and socioeconomic development of ...
Wanjie Zhao, Donglin Li, Yuanjian Wang, Enhui Jiang, Yanhui Liu, Jieyu Li, Qiang Wang   +6 more
doaj   +1 more source

Pollen Aquaporins: the solute factor

Frontiers in Plant Science, 2016
In the recent years, the biophysical properties and presumed physiological role of aquaporins (AQPs) have been expanded to specialized cells where water and solute exchange are crucial traits.
Juliana Andrea Pérez Di Giorgio, Juliana Andrea Pérez Di Giorgio, Gabriela Cynthia Soto, Jorge Prometeo Muschietti, Jorge Prometeo Muschietti, Gabriela Amodeo, Gabriela Amodeo   +6 more
doaj   +1 more source

Hypercalcemia Selectively Decreases Rat Inner Medullary Collecting Duct(IMCD) Vasopressin (AVP)-Elicited Water Permeability (Pf) and Aquaporin-2 (AQP-2) Water Channel Protein Content While Increasing Its Urea Permeability (Purea) and the UT-2 Urea Channel Protein Content • 1650 [PDF]

, 1997
Francisco X. Flores, Akihiko Kato, Michelle A. Baum, Edward M. Brown, Steven Hébert, Jeff M. Sands, H. William Harris   +6 more
openalex   +1 more source

Modeling of water surface profile in non-prismatic compound channels [PDF]

, 2023
Vijay Kumar Kaushik, Munendra Kumar, Bandita Naik, Abbas Parsaie   +3 more
openalex   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Expression and localization of Aquaporin 1a in the sea-bass (Dicentrarchus labrax) during ontogeny

Frontiers in Physiology, 2011
The successful establishment of a species in a given habitat depends on the ability of each of its developing stages to adapt to the environment. In order to understand this process we have studied the adaptation of a euryhaline fish, the sea-bass ...
Ivone eGiffard-Mena, Viviane eBoulo, Charline eAbed, Gordon eCramb, Guy eCharmantier   +4 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source

Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin, Hui‐An Lin, Sheng‐Feng Lin   +2 more
wiley   +1 more source