Results 41 to 50 of about 452,167 (280)

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Robust circadian clock oscillation and osmotic rhythms in inner medulla reflecting cortico-medullary osmotic gradient rhythm in rodent kidney

Scientific Reports, 2017
Circadian clocks in mammals function in most organs and tissues throughout the body. Various renal functions such as the glomerular filtration and excretion of electrolytes exhibit circadian rhythms.
Masayuki Hara, Yoichi Minami, Munehiro Ohashi, Yoshiki Tsuchiya, Tetsuro Kusaba, Keiichi Tamagaki, Nobuya Koike, Yasuhiro Umemura, Hitoshi Inokawa, Kazuhiro Yagita   +9 more
doaj   +1 more source

The Vitruvius' Tale of Archimedes and the Golden Crown [PDF]

, 2011
The paper discusses the tale that we can find in "The Architecture" by Vitruvius, on a method used by Archimedes to determine the percentage of gold and silver in a crown.
Sparavigna, Amelia Carolina
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

The water clock of Proteus mirabilis paces colony periodic and synchronous swarming [PDF]

, 2010
For decades, the origin of the concentric ring pattern of bacterial swarming colonies has puzzled microbiologists. Thanks to _in situ_ and real time infrared microspectroscopy and the brilliance of the infrared beam at SOLEIL synchrotron, we demonstrate ...
Elodie Lahaye, Frederic Jamme, Olivier Sire   +2 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

A Study on an Analysis and Design of the Internal Structure of [PDF]

Journal of Astronomy and Space Sciences, 2017
In this study, the internal structure of a Heumgyeonggak-nu (欽敬閣漏) was designed, and the power transmission mechanism was analyzed. Heumgyeonggak-nu is an automated water clock from the Joseon Dynasty that was installed within Heumgyeonggak (欽敬閣), and ...
Sang Hyuk Kim, Yong-Hyun Yun, Seon Young Ham, Byeong-Hee Mihn, Ho-Chul Ki, Myung-Kyoon Yoon   +5 more
doaj   +1 more source

Ascospore release and survival in Sclerotinia sclerotiorum [PDF]

, 2003
The release and survival of ascospores of a UK Sclerotinia sclerotiorum isolate were studied. Apothecia placed in a spore clock apparatus with different lighting regimes at 15 °C released ascospores continuously with an increasing rate for the duration ...
Abawi, Abawi, Bardin, Boland, Boland, Caesar, Caroline S. Young, Carpenter, Dickson, Grogan, Harthill, Harthill, Huang, Ingold, Ingold, Jayachandran, John M. Whipps, John P. Clarkson, John Staveley, Jones, Kath Phelps, Kosasih, McCartney, Mylchreest, Newton, Partyka, Phillips, Phillips, Raynal, Saito, Sansford, Winston   +31 more
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source