RANCANG BANGUN DAN IMPLEMENTASI SISTEM OTOMATISASI PENYIRAMAN TANAMAN HIDROPONIK MENGGUNAKAN SOLENOID VALVE BERBASIS MIKROKONTROLER AT MEGA 16 [PDF]
Penelitian ini bertujuan untuk merancang monitoring sistem otomatisasi penyiraman tanaman hidroponik supaya lebih efisien dan tidak menggunakan tenaga manusia. Sistem ini terdiri dari perangkat keras dan perangkat lunak.
BAYU AGUS PRASETIYA, 11111100168
core
Why are probabilistic laws governing quantum mechanics and neurobiology?
We address the question: Why are dynamical laws governing in quantum mechanics and in neuroscience of probabilistic nature instead of being deterministic?
Abbot +68 more
core +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Design, Construction, Operation and Performance of a Hadron Blind Detector for the PHENIX Experiment
A Hadron Blind Detector (HBD) has been developed, constructed and successfully operated within the PHENIX detector at RHIC. The HBD is a Cherenkov detector operated with pure CF4.
A. Cherlin +47 more
core +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Improving Crop Water-Use Efficiency Requires Optimizing the Circadian Clock [PDF]
The slogan “more crop per drop,” which was popularized in the early 2000s, depicts the need to improve the productivity of crops for the same water inputs ([Kijne et al., 2003][1]). While the approaches by which this could be achieved have evolved and expanded, the motivation remains ...
openaire +3 more sources
Electronic system for drift clock calculation and synchronization for seafloor observatory [PDF]
The paper describes a new electronic device that allows an easily measurement of the drift between a reference time source (usually GPS) and an atomic rubidium clock which is normally used in seafloor observatories.
Apponi, Umberto +3 more
core
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source

