Results 151 to 160 of about 145,474 (264)

RPLP2 Mediates the Beneficial Effects of Exercise on Stress Resistance Through Muscle–Brain Communication

Advanced Science, EarlyView.
A novel exercise‐inducible myokine acidic ribosomal protein P2 (RPLP2), initially identified from human trials, is presented here, whose circulating levels negatively correlate with clinical anxiety severity. Muscle‐derived RPLP2 enhances hippocampal ribosomal assembly and adult neurogenesis to rescue stress‐induced anxiety deficits.
Peiyu Luo, Wei Wu, Huan Peng, Dan He, Yuxi Guo, Boyue Zhao, Xiaodan Wang, Li Ma, Yuhang Qin, Yifang Zhai, Lixia Zhuo, Ying Zhang, Yijie Guo, Linlin Jing, Fangyao Chen, Erfei Zhang, Wei Wang, Xiancang Ma, Yan Li   +18 more
wiley   +1 more source

Bacillus aryabhattai and silicon modulate soil biological activity and performance of Mimosa caesalpiniifolia under water deficit. [PDF]

Braz J Microbiol
da Silva Mota K, Garcia KGV, de Sousa Almeida M, Barbosa FLA, Borges WL, Mesquita RO, Araujo ASF, de Sousa GG, de Araujo Pereira AP.   +8 more
europepmc   +1 more source

EphB1‐Mediated Transient Blood‐Brain Barrier Opening Facilitates a Ferritin‐Based Nanotherapeutic for Alzheimer's Disease

Advanced Science, EarlyView.
We constructed a brain‐targeted AFn‐DPZ nanodrug delivery system and identified EphB1 as its receptor on the blood‐brain barrier (BBB). This system facilitates drug transport across the BBB and thereby ameliorates cognitive impairment in Alzheimer's disease.
Shilin Wen, Jingjing Gao, Zhixian Wang, Qiumin Ma, Xiao‐Ling Xu, Jianer Chen   +5 more
wiley   +1 more source

Seaweed and melatonin in the induction of tolerance to recurrent water deficit in papaya. [PDF]

Front Plant Sci
Rangel Ferreira T, Tognere Polonini G, Freitas Fonseca L, Tatagiba Franco Brandão C, Ralph Falqueto A, Romais Schmildt E, de Souza Oliveira V, de Oliveira Arantes L, Nascimento de Santana E, Dousseau-Arantes S.   +9 more
europepmc   +1 more source

Sustained Delivery of a Shingles Subunit Vaccine Overcomes Age‐Related Declines in Humoral and Cellular Immunity Relative to Shingrix

Advanced Science, EarlyView.
Sustained delivery of a shingles subunit vaccine from an injectable polymer–nanoparticle hydrogel enhanced the potency, durability, and breadth of immune responses in aged mice while minimizing inflammatory cytokine production and reactogenicity. This strategy decouples immunogenicity from reactogenicity and offers a promising approach to improve ...
Ye Eun Song, Jerry Yan, Ben S. Ou, Olivia M. Saouaf, Noah Eckman, E. A. Appel   +5 more
wiley   +1 more source

Water deficit modulates growth, secondary metabolism, and carvacrol biosynthesis gene expression in <i>Plectranthus amboinicus</i> (Lour.) Spreng. [PDF]

Physiol Mol Biol Plants
El-Sheshtawy AN, Dahab A, Bayomy H, Almasoudi S, Youssef S, Zulfiqar F, El-Ghany TA, El-Serafy R, Elshayeb N.   +8 more
europepmc   +1 more source

Functionalized Biomimetic Scaffolds for Human‐Derived Auditory Neural Circuit Construction

Advanced Science, EarlyView.
In Vitro Auditory Circuit Model. ABSTRACT Damage to auditory circuits results in sensorineural hearing loss. However, the scarcity of human inner ear tissue significantly hinders the development of therapies to preserve auditory function, creating a critical need for reliable in vitro models.
Pan Feng, Qian Zhu, Yusong Wang, Hao Rong, Xu Zhang, Fuchun Wang, Tianqi Yu, Wenxuan Wang, Jing Li, Lei Tian, Menghui Liao, Renjie Chai, Yangnan Hu   +12 more
wiley   +1 more source

Scion-Rootstock interactions shape early transcriptional responses to controlled water deficit in newly selected table grape genotypes. [PDF]

BMC Plant Biol
Maggiolini FAM, Santamaria M, Bergamini C, Marsico AD, Basile T, Forleo LR, Prencipe A, Perniola R, D'Amico M, Cardone MF.   +9 more
europepmc   +1 more source

Targeted Degradation of STING by a Neutrophil Membrane‐Coated Nanoplatform Suppresses Microglial Pyroptosis After Subarachnoid Hemorrhage

Advanced Science, EarlyView.
MG1@NM‐Px serves as a microglia‐targeted STING‐degrading nanoplatform for subarachnoid hemorrhage. Following systemic administration, it crosses the blood–brain barrier and accumulates in activated microglia. STP1‐mediated STING ubiquitination and degradation suppress MAPK/inflammasome signaling, GSDME‐mediated pyroptosis, and IL‐1β release, revealing ...
Ruotian Zhang, Kaikun Yuan, Haoyu Zou, Hanfeng Qin, Jiale Liu, Jianda Sun, Feifan Zhang, Yuankui Wang, Tong Wang, Jiaxing Dai, Chunxu Li, Yichi Chen, Yingfeng Tu, Huaizhang Shi   +13 more
wiley   +1 more source

Tolerance and Antioxidant Activity of Watermelon Cultivars Pre-Treated with Stress Attenuators and Subjected to Water Deficit. [PDF]

Plants (Basel)
Leite MS, Torres SB, Benedito CP, Pereira KTO, Arruda MVM, Oliveira RR, Sousa GD, Albuquerque CC, Morais MB, Alves CZ, Silva GZD, Sousa EM, Silva PFD, Martins CC, Sá FVDS.   +14 more
europepmc   +1 more source