Results 171 to 180 of about 145,474 (264)

Self‐Assembly of Antigenic Peptide Nanofibrils Templates the Growth of Silica Nanoparticles for Nanovaccines

Advanced Science, EarlyView.
Antigenic peptides Aβ42 and E7 self‐assemble into nanofibrils; APTES and TEOS induce SiO2 NP formation on these fibrils to form SiO2@fibril nanovaccines, which activate BMDCs in vitro. In vivo, SiO2@Aβ42 fibril nanovaccines alleviate AD symptoms and clear Aβ42 plaques in APP/PS1 mice, and SiO2@E7 fibril nanovaccines inhibit tumor growth and promote ...
Xuecheng Yang, Min Li, Zhiying Yao, Yu Hu, Zhili Wang, Wendi Shi, Bingbing Sun   +6 more
wiley   +1 more source

Canopy Carbon- and Water-Use Efficiencies in Response to Temperature and Water Deficit for Wheat. [PDF]

Plant Cell Environ
Fang L, Struik PC, Yin X, Martre P.
europepmc   +1 more source

Revolutionising Agricultural Sustainability: New ‘Furrow Tillage’ can Mitigate Short‐Term Soil‐to‐Atmosphere CO2 Flux and Promote Soil‐Plant‐Microbe Health

Advanced Science, EarlyView.
Furrow tillage resolves the conventional‐vs.‐no‐tillage trade‐off by simultaneously cutting CO2 efflux to 2.0–3.0 g C m−2 d−1 and unlocking high nutrient availability for the rice rhizosphere. This scalable agronomic solution strengthens soil health, enhances plant physiology, reshapes microbial metabolism, and shifts paddy systems toward a net ...
Arnab Majumdar, Munish Kumar Upadhyay, Argha Ghosh, Rakesh Biswas, Ioly Kotta Loizou, Martin Buck, Mark Tibbett, Biswajit Giri, Debojyoti Moulick, Manoj Kumar Jaiswal, Tarit Roychowdhury   +10 more
wiley   +1 more source

Salicylic Acid Mitigates the Effects of Water Deficit in Sour Passion Fruit in the Phenological Phases. [PDF]

Plants (Basel)
Souza AR, Soares de Lima G, Rodrigues da Silva AA, Vieira de Azevedo CA, Araújo Borborema LD, Gomes Nunes K, Costa DS, Souza Santos LF, de Lima Arruda TF, Fallé Saboya LM, Almeida Dos Anjos Soares L, Raj Gheyi H, Belo de Souza WB, Lemos da Silva FJ, de Oliveira Porto G.   +14 more
europepmc   +1 more source

Therapeutic Gene Editing of APOE4 in Sporadic Alzheimer's Disease via Prime Editor 7

Advanced Science, EarlyView.
Prime Editor 7‐mediated conversion of APOE4 to APOE3 alleviates Alzheimer's disease‐associated pathology in AD mouse models and patient‐derived neurons and improves cognitive performance in vivo, supporting therapeutic genome editing as a promising strategy for APOE4‐associated neurodegeneration.
Yunkyung Kim, Gaeun Lee, Saemin An, Hanseul Park, Hongwon Kim, Jisung Kim, Soi Kang, Sumin Kim, Daeyeol Kwon, Jeonghyun Park, Yerim Hwang, Seonghun Kim, Xiuwen Yuan, Jaehoon Jeong, Hamin Lee, Hui Kwon Kim, Jongpil Kim   +16 more
wiley   +1 more source

Alleviation of water-deficit inhibition of plant growth by rhizosphere microbiota conditioning. [PDF]

New Phytol
Angot V, Thiour-Mauprivez C, Schellenberger R, Lamboeuf M, Crépin O, Garmyn D, Blouin M, Jacquiod S.   +7 more
europepmc   +1 more source

HD‐tDCS Restores Perivascular AQP4 Polarization via PPARγ Modulation to Enhance Glymphatic Clearance After Intracerebral Hemorrhage in Mice

Advanced Science, EarlyView.
HD‐tDCS promotes recovery after intracerebral hemorrhage by enhancing PPARγ‐dependent astrocyte remodeling in a mouse model of ICH. This process suppresses proinflammatory astrocytic activation, restores perivascular AQP4 repolarization, and improves glymphatic influx and efflux, thereby facilitating hematoma and perihematomal edema clearance and ...
Zhiming Li, Yingmei Zhang, Qianqian Tong, Zhitao Gong, Shanyu Zhang, Zhen Qian, Hui Zhang, Qian Yao, Qi Li   +8 more
wiley   +1 more source

Single-cell proteomics of Arabidopsis leaf mesophyll reveals dynamic protein responses to water-deficit stress. [PDF]

Genome Biol
Fulcher JM, Dawar P, Balasubramanian VK, Williams SM, Nadeau KD, Winkler TE, Markillie LM, Mitchell HD, Ahkami AH, Paša-Tolić L, Zhu Y.   +10 more
europepmc   +1 more source

Gut Microbial Release of Ferulic Acid From Germinated Quinoa Alleviates Obesity‐Associated Cognitive Impairment by Activating Hippocampal Mitophagy Associated with PINK1/Parkin Pathway

Advanced Science, EarlyView.
Liberation of ferulic acid by gut microbial feruloyl esterase mediates cognitive enhancement of germinated quinoa (GQF) on obese mice. Ferulic acid enriched in GQF is released by gut microbes Roseburia hominis and R. intestinalis and subsequently mediates the neuroprotective effects of GQF on obesity‐induced cognitive decline by activating hippocampal ...
Yongli Lan, Wengang Zhang, Lei Wang, Shiyang Zhao, Yujie Song, Xinze Wang, Yutang Wang, Xijuan Yang, Shaobo Ma, Junlin Ge, Rui Guo, Xuebo Liu   +11 more
wiley   +1 more source

Physiological and Proteomic Responses of Sugarcane to Water Deficit Stress: Insights from a Self-Fertilized Clone. [PDF]

Int J Mol Sci
Dutra Filho JA, Barbosa Neto AG, Pacheco Ladislau CM, Silva MAD, Rocha GMGD, Luna RG, Souza ADS, Souto LS, de Oliveira Gondim AR, Porto ACF, Cavalcante Silva FA, Vasconcelos JM, Rocha Moreira G, Neder DG, Alvino FCG, Alves LS, Freitas LC, Neto DES, Menossi M, Calsa Junior T.   +19 more
europepmc   +1 more source