Results 61 to 70 of about 1,636,028 (309)
Neyman-Scott-based water distribution network modelling
Ingeniería e Investigación, 2012 Residential water demand is one of the most difficult parameters to determine when modelling drinking water distribution networks. It has been proven to be a stochastic process which can be characterised as a series of rectangular pulses having set ...
Víctor Hugo Alcocer Yamanaka +1 more
doaj
Water Use Efficiency Current Status Assessment in the Context of WATenERgy CYCLE Project
Proceedings, 2018 Water use efficiency is a crucial issue in drinking water utilities as it is connected to environmental and economic consequences. WATenERgy CYCLE project aims at developing a methodological approach towards efficient and effective transnational water ...
Stavroula Tsitsifli +3 more
doaj +1 more source
Strategic Management of Separation of Drinking Water from Sanitation Water in the City of Yazd by Using AHP and SWOT Analysis [PDF]
آب و فاضلاب, 2019 In the current situation, water resources are facing quantitative and qualitative issues which leave us with no other choice except to change our perspective towards consumption management.
Farzaneh Fotouhi Firoozabad +3 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Failures analysis of water distribution network during 2006-2008 in Ahvaz, Iran [PDF]
Journal of Advances in Environmental Health Research, 2013 Failures in the water distribution network are some most important factors in water losses, water shortage and dissatisfaction of users and secondary pollutions as well.
Mehdi Ahmadi +3 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Evaluation of Municipal Water Distribution System Reliability Using Minimum Cut-set Method
Journal of King Saud University: Engineering Sciences, 2005 Reliability analysis of water distribution systems is a complex task, as it requires both definition and calculation of reliability measures. In this paper, a methodology for evaluating water distribution system reliability is developed and demonstrated ...
Muhammad A. Al-Zahrani, Juned Laiq Syed
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source