Results 71 to 80 of about 416,143 (217)

Intelligent Pressure Management to Reduce Leakage in Urban Water Supply Networks, A Case Study of Sarafrazan District, Mashhad [PDF]

open access: yesآب و فاضلاب, 2009
Water losses are inevitable in urban water distribution systems. The two approaches adopted nowadays to combat this problem include management of hydraulic parameters such as pressure and leakage detection in the network. Intellitgent pressure management
Mohammad Soltani Asl   +1 more
doaj  

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang   +10 more
wiley   +1 more source

Strategies for Improving the Resiliency of Distribution Networks in Electric Power Systems during Typhoon and Water-Logging Disasters

open access: yesEnergies
Coastal cities often face typhoons and urban water logs, which can cause power outages and significant economic losses. Therefore, it is necessary to study the impact of these disasters on urban distribution networks and improve their flexibility.
Nan Ma   +8 more
doaj   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett   +8 more
wiley   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao   +6 more
wiley   +1 more source

Predictive Modeling the Turbidity Response in Al-Saray Water Distribution Network in Najaf Governorate/Middle of Iraq, Using PODDS Model

open access: yesCivil and Environmental Engineering
Reducing water turbidity is one of the main issues the water industry is currently experiencing. The ability to predict the spatial probability and intensity of discoloration events in distribution systems can lead to the adoption and improvement of ...
Abed Zahraa H.   +2 more
doaj   +1 more source

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