Results 51 to 60 of about 13,452,782 (251)

Characterizing microbial processes during drinking water production and distribution [Kralingen water treatment plant and distribution network]

open access: yes, 2014
The main objective for water treatment companies is to produce and supply water that is safe, free from any pathogenic microorganisms and biologically stable. In the recent years, problems related to disinfection byproducts (e.g., carcinogenic THMs) were
Sotywambe, Fezeka
core   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

Evaluation of Municipal Water Distribution System Reliability Using Minimum Cut-set Method

open access: yesJournal of King Saud University: Engineering Sciences, 2005
Reliability analysis of water distribution systems is a complex task, as it requires both definition and calculation of reliability measures. In this paper, a methodology for evaluating water distribution system reliability is developed and demonstrated ...
Muhammad A. Al-Zahrani, Juned Laiq Syed
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

On-line monitoring for operational control of water distribution networks [PDF]

open access: yes, 1992
This work concerns the concept of on-line monitoring and control for water distribution networks. The problem is simple to state. It is to produce a robust scheme that can continuously provide reliable information about the state of a water network in ...
Powell, R.S., Powell, R
core  

A multiobjective optimization framework for multicontaminant industrial water network design. [PDF]

open access: yes, 2011
The optimal design of multicontaminant industrial water networks according to several objectives is carried out in this paper. The general formulation of the water allocation problem (WAP) is given as a set of nonlinear equations with binary variables ...
Montastruc, Ludovic   +9 more
core   +1 more source

EVALUASI DEBIT DAN TEKANAN MELALUI SIMULASI KEBUTUHAN AIR PADA JARINGAN PIPA DISTRIBUSI AIR BERSIH KOTA KANDANGAN PROPINSI KALIMANTAN SELATAN

open access: yesTeknologi dan Kejuruan, 2012
: Evaluation of Flow and Pressure Using Water Requirement  Simulation on Water  Distribution system in Kandangan, South Kalimantan. Certain locations in service region of clean water network pipe in Kandangan city South Kalimantan profince still ...
Rony Riduan   +2 more
doaj   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

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