Results 31 to 40 of about 11,715,296 (244)

Modeling and optimization of pressure and water age for evaluation of urban water distribution systems performance

open access: yesHeliyon, 2022
Water loss has become increasingly critical as the severity of the water shortage situation has grown in recent decades. One of the options for reducing water loss in urban water distribution networks is pressure management.
Wendesen Mekonin Desta   +2 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

On-line monitoring for operational control of water distribution networks [PDF]

open access: yes, 1992
This work concerns the concept of on-line monitoring and control for water distribution networks. The problem is simple to state. It is to produce a robust scheme that can continuously provide reliable information about the state of a water network in ...
Powell, R.S., Powell, R
core  

Interpretable event diagnosis in water distribution networks

open access: yesIntelligent Systems with Applications
The increasing penetration of information and communication technologies in the design, monitoring, and control of water systems enables the use of algorithms for detecting and identifying unanticipated events (such as leakages or water contamination ...
André Artelt   +5 more
doaj   +1 more source

Reliability based rehabilitation of water distribution networks by means of Bayesian networks

open access: yesJournal of Water and Land Development, 2017
Water plays an essential role in the everyday lives of the people. To supply subscribers with good quality of water and to ensure continuity of service, the operators use water distribution networks (WDN). The main elements of water distribution network (
Lakehal Abdelaziz, Laouacheria Fares
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Hydraulic modelling of intermittent water supply using the DMA concept for equitable water distribution

open access: yes, 2020
Water scarcity is increasingly becoming a great concern in both developed and developing countries. Fuelled by the increasing effects of climate change, rapid population growth, rapid urban development and urban migration, demand for potable water is ...
Otieno, Samuel Odhiambo
core   +1 more source

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