Results 51 to 60 of about 11,715,296 (244)

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

The effect of building storage tanks on diurnal flow variation in water distribution networks

Applied Water Science
The peak hour factor is commonly used in the analysis and design of water distribution networks as a function of population. However, water storage tanks in buildings significantly influence diurnal flow variations of these networks, yet their impact has
Ramtin Mazaheri, Homayoun Motiee, Mohammadreza Jalili Ghazizadeh   +2 more
doaj   +1 more source

Energy Saving Measures in Pressurized Irrigation Networks: A New Challenge for Power Generation

Proceedings, 2018
In Spain and other countries, open channel distribution networks have been replaced by on demand-pressurized networks to improve the water-use efficiency of the water distribution systems, but at the same time the energy requirements have dramatically ...
Jorge García Morillo, Juan A. Rodríguez Díaz, Miguel Crespo, Aonghus McNabola   +3 more
doaj   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

A Parameter Classification System for Nonrevenue Water Management in Water Distribution Networks

Advances in Civil Engineering, 2018
Nonrevenue water (NRW) in a water distribution network is the water lost from unbilled authorized consumption, apparent losses, and real losses compared to the total system input volume.
Dongwoo Jang
doaj   +1 more source

Improvement of water distribution networks analysis by topological similarity

Alexandria Engineering Journal, 2016
In this research paper a methodology based on topological similarity is used to obtain starting point of iteration for solving reservoir and pipe network problems.
Mahavir Singh, Suraj Krishan Kheer, I.K. Pandita   +2 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Physics-Informed Machine Learning for Universal Surrogate Modelling of Water Quality Parameters in Water Distribution Networks

Engineering Proceedings
Modelling and assessing water quality parameters in water distribution networks is essential for providing safe drinking water to end users. While simulation-based modeling approaches rely on costly differentiation for numerical solvers, surrogate models
Ivo Daniel, Gopinathan R. Abhijith, J. Nathan Kutz, Avi Ostfeld, Andrea Cominola   +4 more
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source