Results 51 to 60 of about 225,214 (264)

Rapid surrogate modelling of water-hammer in water distribution networks using spatiotemporal graph convolutional networks

open access: yesEngineering Applications of Computational Fluid Mechanics
Safe drinking water is essential to public health and social stability. Despite advances in modern materials and design, water distribution systems (WDSs) remain vulnerable to failure.
Minhyuk Jeung   +3 more
doaj   +1 more source

Energy Saving Measures in Pressurized Irrigation Networks: A New Challenge for Power Generation

open access: yesProceedings, 2018
In Spain and other countries, open channel distribution networks have been replaced by on demand-pressurized networks to improve the water-use efficiency of the water distribution systems, but at the same time the energy requirements have dramatically ...
Jorge García Morillo   +3 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

The effect of building storage tanks on diurnal flow variation in water distribution networks

open access: yesApplied Water Science
The peak hour factor is commonly used in the analysis and design of water distribution networks as a function of population. However, water storage tanks in buildings significantly influence diurnal flow variations of these networks, yet their impact has
Ramtin Mazaheri   +2 more
doaj   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Improvement of water distribution networks analysis by topological similarity

open access: yesAlexandria Engineering Journal, 2016
In this research paper a methodology based on topological similarity is used to obtain starting point of iteration for solving reservoir and pipe network problems.
Mahavir Singh   +2 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Physics-Informed Machine Learning for Universal Surrogate Modelling of Water Quality Parameters in Water Distribution Networks

open access: yesEngineering Proceedings
Modelling and assessing water quality parameters in water distribution networks is essential for providing safe drinking water to end users. While simulation-based modeling approaches rely on costly differentiation for numerical solvers, surrogate models
Ivo Daniel   +4 more
doaj   +1 more source

A Parameter Classification System for Nonrevenue Water Management in Water Distribution Networks

open access: yesAdvances in Civil Engineering, 2018
Nonrevenue water (NRW) in a water distribution network is the water lost from unbilled authorized consumption, apparent losses, and real losses compared to the total system input volume.
Dongwoo Jang
doaj   +1 more source

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