Results 131 to 140 of about 2,415,663 (305)

The ineffectiveness of current environmental and fire policies in the world’s largest wetland

Environmental Research Letters
The Upper Paraguay Basin (UPRB) covers 361 338 km ^2 in Brazil and can be divided into the Planalto (plateau) and the Pantanal, the largest wetland in the world.
Lucas Barros-Rosa, Luiza Moura Peluso, Priscila Lemes, Mark Stephen Johnson, Higo José Dalmagro, Cátia Nunes da Cunha, Paulo Henrique Zanella de Arruda, Lúcia Mateus, Jerry Penha   +8 more
doaj   +1 more source

Surge Instability on a Cavitating Propeller [PDF]

, 2000
This study details experiments investigating a previously unrecognized surge instability on a cavitating propeller in a water tunnel. The surge instability is explored through visual observation of the cavitation on the propeller blades and in the tip ...
Brennen, C. E., Duttweiler, M. E.
core   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Dynamics of Supercooled Water and Glassy Water

hamon, 2004
Quasielastic neutron scattering of normal and supercooled water was measured in the temperature range 253-330K to investigate the possible anomaly expected to occur around 230K. Anomalous temperature dependence of self-diffusion coefficient, which may suggest a critical slowing-down, was found for the first time. Vapor-deposited glassy water (amorphous
openaire   +2 more sources

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

Degradation and defluorination of perfluorooctane sulfonate (PFOS) forever chemical in water using hydrodynamic cavitation treatment

Chemical Engineering Journal Advances
Per- and polyfluoroalkyl substances (PFAS), also known as ''forever chemicals,'' are persistent environmental contaminants that pose significant risks to human health and aquatic ecosystems.
Amit Kumar, Anett Georgi, Ysabel Huaccallo-Aguilar, Markus Meier, Holger Kryk, Sebastian Felix Reinecke, Uwe Hampel   +6 more
doaj   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Climate-resilient systems prioritisation index: a spatial framework for multi-hazard mitigation via nature-based solutions

Geomatics, Natural Hazards & Risk
This article presents the Climate-Resilient Systems Prioritisation Index (CRESPI), a GIS-based spatial decision-support framework developed to support climate resilience planning through the prioritisation of Nature-based Solutions (NbS).
Katerina Tzavella, Yuting Tai, Paula Janeka, Matthias Schupp, Sara Pino Cobacho, Liesa Brosens, Bastiaan Notebaert, Mindert de Vries   +7 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source