Results 71 to 80 of about 784,267 (315)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Water is not a dynamic polydisperse branched polymer [PDF]

Proceedings of the National Academy of Sciences, 2019
The contributed paper by Naserifar and Goddard reports that their RexPoN water model under ambient conditions simulates liquid water as a dynamic polydisperse branched polymer, which they speculate explains the existence of the liquid-liquid critical point (LLCP) in the supercooled region.
Teresa Head-Gordon, Francesco Paesani
openaire   +5 more sources

Computational Fluid Dynamics Modelling of Flocculation in Water Treatment: A Review [PDF]

, 2009
The principal focus of this paper is to present a critical review of current approaches to modelling the inter-related hydrodynamic, physical and chemical processes involved in the flocculation of water using Computational Fluid Dynamics (CFD).
Jefferson, B, Jefferson, Bruce, Parsons, Simon A., Bridgeman, Jonathan, Bridgeman, J., Parsons, SA   +5 more
core   +1 more source

A Simulation Experiment on Quality Dynamics of Reclaimed Water under Different Flow Exchanges [PDF]

, 2022
Reclaimed water plays an important role in maintaining urban aquatic ecosystems, especially in areas with water shortages. However, there is little information on water quality dynamics and its driving mechanism in reclaimed water bodies.
Chengzhong Pan, Pan, Chengzhong, Luo, Mingjie, Guo, Zhongfang, Mingjie Luo, Zhongfang Guo   +5 more
core   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Water Dynamics in Polyacrylamide Hydrogels

Journal of the American Chemical Society, 2018
Polymeric hydrogels have wide applications including electrophoresis, biocompatible materials, water superadsorbents, and contact lenses. The properties of hydrogels involve the poorly characterized molecular dynamics of water and solutes trapped within the three-dimensional cross-linked polymer networks.
Chang Yan, Patrick L. Kramer, Rongfeng Yuan, Michael D. Fayer   +3 more
openaire   +3 more sources

Simulating the fast transport of water through carbon nanotubes [PDF]

, 2011
Non-equilibrium molecular dynamics simulations are performed to investigate water transport through (7,7) CNTs and to examine how changing the CNT length affects the flow dynamics.
Borg, M.K., Nicholls, W.D., Borg, Matthew Karl, Nicholls, William, Reese, J.M., Reese, Jason   +5 more
core  

Role of cationic organisation on water dynamics in saponite clays [PDF]

, 2023
Water dynamics impacts many phenomena from geosciences to biology, especiallly in confined environments. In the presence of charged interfaces, there are some ions the role of which with regards to the water dynamics is unclear. Here a synthetic saponite
Sébastien, Le Crom, Virginie, Marry, Bela, Farago, Alfred, Delville, Eric , Ferrage, Emmanuelle, DUBOIS, Laurent, Michot   +6 more
core   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source