Results 121 to 130 of about 372,230 (299)
Predicting dive start performance from kinematic variables at water entry in (sub-)elite swimmers. [PDF]
PLoS One, 2020 van Dijk MP, Beek PJ, van Soest AJK.
europepmc +1 more source
Poster: Neighbors of water entry [PDF]
74th Annual Meeting of the APS Division of Fluid Dynamics - Gallery of Fluid Motion, 2021 Akihito Kiyama +3 more
openaire +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
A Review of Experimental and Numerical Research on the Slamming Problem of High-Performance Vessels
Journal of Marine Science and EngineeringSlamming load is characterized by a high peak and short duration. Severe slamming phenomena are extremely detrimental to the navigation safety of high-speed vessels, thereby constraining the development and application of high-performance ships.
Yifang Sun +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Entry regulation and business start-ups : evidence from Mexico [PDF]
The authors estimate the effect on business start-ups of a program that significantly speeds up firm registration procedures. The program was implemented in Mexico in different municipalities at different dates.
Seira, Enrique +2 more
core
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Shallow angle water entry of ballistic projectiles [PDF]
, 2009 The water-entry of ballistic projectiles is investigated using high-speed digital imaging to capture the subsurface cavity dynamics. Specially designed 0.22 caliber projectiles are fired into water at shallow angles to the free surface (5º to 15º) at ...
Techet, A., Beal, D., Truscott, T.
core
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source