Results 111 to 120 of about 549,261 (292)

IWMI Strategic plan 2009-2013: water for a food-secure world [PDF]

open access: yes
Strategy planning / Research institutes / Institutional development / Research priorities / Water resource management / Water ...
International Water Management Institute (IWMI).
core  

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Water governance in the Mekong region: the need for more informed policy-making [PDF]

open access: yes
Water management / River basins / Governance / Policy making / Planning / Water law / South East Asia / China / Vietnam / Cambodia ...
International Water Management Institute (IWMI).
core  

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Irrigation and water policies in the Mekong region: current discourses and practices [PDF]

open access: yes
Water resource management / Water policy / Water law / Participatory management / Irrigation management / River basins / Governance / South East Asia / Thailand / Cambodia / Laos / Vietnam / Myanmar / China / Mekong ...
Molle, Francois
core  

GLAAS 2014 Findings: Special report for Africa [PDF]

open access: yes, 2015
The UN-Water GLAAS Special Report for Africa, an initiative led by WHO in close collaboration with the African Ministers' Council on Water and the African Development Bank, provides data from 39 African countries to take stock on progress made during the

core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Informal water suppliers meeting water needs in the peri-urban areas of Mumbai, India [PDF]

open access: yes
This paper is based on fieldwork on the small-scale water providers in the peri-urban areas of Mumbai. It tries to explain why small-scale water providers have appeared there, what type of service they provide and why they have succeeded, where the ...
Anastasia Angueletou-Marteau
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

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