Results 41 to 50 of about 40,095 (264)
Key Challenges and Strategic Pathways for Improving Municipal Drinking Water Quality
能源环境保护Ensuring drinking water safety is critical to public welfare, directly impacting public health and social stability. In China, rapid economic development and continuous improvement of living standards have led to an increasing demand for high-quality ...
Chao ZENG +3 more
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Migration Patterns and Prevention and Control Strategies for Microplastics under Reservoir Scheduling [PDF]
长江科学院院报[Objective] Microplastics are widely present in reservoirs across China, posing threats to water quality safety and the stability of reservoir ecological functions.
CHEN Yu-ling, LIN Li
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FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Earth System GovernanceThe recognition of the Mar Menor as a subject of rights under Spanish Law 19/2022 marked the first instance in Europe of granting legal personhood to an ecosystem. This article provides a critique of this unprecedented measure by examining its doctrinal,
Francisco Pérez-Crespo Vinader +2 more
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Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
WATER GOVERNANCE IN THE SMART CITY [PDF]
WIT Transactions on The Built Environment, 2018 LIFE project LIFE15 ENV/ES/000598 “Development of an efficient and sustainable methodology for emerging pollutants removal in WWTPs” (1/09/2016–31/08/2019).
openaire +2 more sources
Escalating overtopping risk in dams during wartime: the case of Jebel Aulia Dam, Sudan
Environmental Research CommunicationsAcross the world, conflicts have disrupted dam operations, leading to water mismanagement and increased disaster potential. This study uses water balance modelling and scenario analysis to present a replicable framework for assessing flood risks in ...
Aseel Mohamed +2 more
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The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source