Results 41 to 50 of about 556,228 (310)

Water governance and institutional change [PDF]

open access: yes, 2004
This dissertation is about water governance and institutional change. The focus on water governance means that we are interested in collective action with respect to water issues, which is not restricted to government action by public authorities, but ...
Kuks, S.M.M.
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Not quite what’s on paper? Comparison between theoretical and actual information-sharing networks in the Ugandan rural water service sector [PDF]

open access: yes, 2019
Under Uganda’s decentralised system, rural water service delivery remains to some extent problematic. Several studies attribute the possible causes of deficiencies in the water sector to governance issues.
Nathalie Holvoet   +2 more
core   +2 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Adaptive spatial-channel feature fusion and self-calibrated convolution for early maize seedlings counting in UAV images

open access: yesFrontiers in Plant Science
Accurate counting of crop plants is essential for agricultural science, particularly for yield forecasting, field management, and experimental studies. Traditional methods are labor-intensive and prone to errors.
Zhenyuan Sun   +14 more
doaj   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Migration Patterns and Prevention and Control Strategies for Microplastics under Reservoir Scheduling [PDF]

open access: yes长江科学院院报
[Objective] Microplastics are widely present in reservoirs across China, posing threats to water quality safety and the stability of reservoir ecological functions.
CHEN Yu-ling, LIN Li
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Taming the Floods: Using an Intellectual History of Chinese Hydraulic Thought to Address Contemporary Issues in China’s Water Governance [PDF]

open access: yes, 2018
China’s current hydraulic systems are in a state of atrophy, caused by sustained damage over centuries to infrastructure that has changed very little. Added to an already weak infrastructure is a relatively new crisis of water scarcity, which is forcing ...
Danison, Sophia Rose
core   +1 more source

The pyruvate generator is a common phenomenon in mitochondria from different rat and mouse brain regions

open access: yesFEBS Letters, EarlyView.
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy