Results 61 to 70 of about 37,245 (263)

Risk of real-time irrigation decision-making system for farmland in arid irrigation districts: Methodology and case studyMendeley Data

open access: yesAgricultural Water Management
Making precise irrigation decisions several days in advance is of great significance for improving water resource utilization efficiency in arid regions.
Yimin Ding   +5 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Effects of a composite phosphate corrosion inhibitor on corrosion behavior and water quality stability in drinking water distribution systems

open access: yesWater Cycle
This study investigated the effectiveness of a composite phosphate corrosion inhibitor in enhancing water quality stability in drinking water distribution systems (DWDSs), guided by practical engineering needs.
Zhu Peng   +5 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Impact of Three Gorges Project Impoundment on Spatiotemporal Variation of Pollutant Flux in Mainstream Yangtze River [PDF]

open access: yes长江科学院院报
[Objective] To investigate the variation patterns of pollutant fluxes in the Yangtze River mainstream before and after the operation of the Three Gorges Project, this study analyzes the annual variations in water quality, runoff, and pollutant fluxes at ...
PENG Lian, ZHAO Min, QIAN Bao, ZHOU Bing-yi
doaj   +1 more source

A systematic review on the role of trust in the water governance literature. [PDF]

open access: yesWater Res X, 2022
Voogd R   +9 more
europepmc   +1 more source

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