Results 61 to 70 of about 556,228 (310)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Estimating and forecasting daily reference crop evapotranspiration in China with temperature-driven deep learning modelsMendeley Data

Agricultural Water Management
Accurately estimating and forecasting short-term daily reference crop evapotranspiration (ETo) is crucial for real-time irrigation decision-making and regional agricultural water management.
Jia Zhang, Yimin Ding, Lei Zhu, Yukuai Wan, Mingtang Chai, Pengpeng Ding   +5 more
doaj   +1 more source

Governing in the Anthropocene: What Future Systems Thinking in Practice? [PDF]

, 2016
The revealing and concealing features of the metaphor ‘earth as Anthropocene’ are explored in an inquiry that asks: In the Anthropocene what possible futures emerge for systems thinking in practice? Framing choice, so important yet so poorly realised, is
Alstyne, Armitage, Ashby, Baird, Baird, Bateson, Beer, Biermann, Bommel, Boulding, Checkland, Checkland, Checkland, Checkland, Cook, Crutzen, Hubert, Ison, Ison, Ison, Ison, Ison, Ison, Ison, Ison, Jasanoff, Jones, Lakoff, Lakoff, Lakoff, Lakoff, Larsen, LEARN, Lourdes Melo Zurita, Malm, McClintock, McClintock, Meadows, Micklethwait, Moll, Norgaard, Open University, Powell, Russell, Russell, Sankaran, Schön, Steirlin, Steyaert, Stowell, Straw, Thompson, Tingle, Tsien, Westberg, Wiener   +55 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

A probabilistic deep learning approach to enhance the prediction of wastewater treatment plant effluent quality under shocking load events

Water Research X
Sudden shocking load events featuring significant increases in inflow quantities or concentrations of wastewater treatment plants (WWTPs), are a major threat to the attainment of treated effluents to discharge quality standards.
Hailong Yin, Yongqi Chen, Jingshu Zhou, Yifan Xie, Qing Wei, Zuxin Xu   +5 more
doaj   +1 more source

Agricultural water management in Bulgaria [PDF]

This paper analyzes evolution and efficiency of water governance in Bulgarian agriculture during post-communist transition and EU integration. First, it defines the water governance and the scope of analysis.
Bachev, Hrabrin
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Performance comparison of a solar parabolic trough concentrator using different shapes of linear cavity receiver

Case Studies in Thermal Engineering
This study presents a numerical investigation of a solar Parabolic Trough Concentrator (PTC) with various Linear Cavity Receivers (LCRs). A linear trapezoidal cavity receiver was simulated and analyzed optically and thermally in the PTC system.
Reyhaneh Loni, Mahdi Sharifzadeh
doaj   +1 more source

Modelling Iniltration in A Large Scale Paddy Field in Malaysia

IEM Journal, 2016
A number of models are available to measure infiltration in agricultural fields; however, their applicability is site specific. It is not easy to choose an adequate model to estimate infiltration at a particular agricultural field.
Prof. Dr Md. Hazrat Ali, Ir. Dr Ayob Katimon, Biswa Bhattacharya   +2 more
doaj   +1 more source