Results 61 to 70 of about 40,095 (264)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Risk of real-time irrigation decision-making system for farmland in arid irrigation districts: Methodology and case studyMendeley Data

Agricultural Water Management
Making precise irrigation decisions several days in advance is of great significance for improving water resource utilization efficiency in arid regions.
Yimin Ding, Mingyu Wang, Jianxin Jin, Zhengyuan Sun, Jia Zhang, Lei Zhu   +5 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Effects of a composite phosphate corrosion inhibitor on corrosion behavior and water quality stability in drinking water distribution systems

Water Cycle
This study investigated the effectiveness of a composite phosphate corrosion inhibitor in enhancing water quality stability in drinking water distribution systems (DWDSs), guided by practical engineering needs.
Zhu Peng, Tian-Yang Zhang, Jian Ai, Ren-Jie Pan, Dai-Xu Zhang, Bin Xu   +5 more
doaj   +1 more source

Decolonising Canadian water governance: lessons from Indigenous case studies. [PDF]

UCL Open Environ, 2023
McKibbin C.
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Theoretical connotations, practical obstacles, and governance pathways of China's “three-water coordination” in new era [PDF]

Ziyuan Kexue
[Objective] The concept of “three-water coordination” emphasizes the systematic coordination of water resources, water environment, and aquatic ecosystems.
LI Jialin, TIAN Peng, LIU Yongchao, GONG Hongbo, YING Chao
doaj   +1 more source

Engagement in water governance action situations in the Lake Champlain Basin. [PDF]

PLoS One, 2023
Bitterman P, Koliba C.
europepmc   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

A systematic review on the role of trust in the water governance literature. [PDF]

Water Res X, 2022
Voogd R, Rudberg PM, de Vries JR, Beunen R, Espiritu AA, Methner N, Larsen RK, Fedreheim GE, Goes S, Kruger E.   +9 more
europepmc   +1 more source