Results 81 to 90 of about 40,095 (264)

Adaptive Water Governance: Integrating the Human Dimensions into Water Resource Governance [PDF]

open access: yesJournal of Contemporary Water Research & Education, 2016
AbstractThe command‐and‐control paradigm of water resource management that dominated 20th century water policy has resulted in vulnerabilities due to its inadequate consideration of the human dimensions as well as its failure to prioritize the need for learning and adapting to change and uncertainties. In response to these shortfalls, recent years have
openaire   +1 more source

Modeling water flow and volumetric water content in a degraded peat comparing unimodal with bimodal porosity and flux with pressure head boundary condition

open access: yesVadose Zone Journal
Degraded peatlands release large amounts of greenhouse gases. The development of effective mitigation and management measures requires an understanding of relevant site‐specific biogeochemical and hydraulic processes.
Mariel F. Davies   +3 more
doaj   +1 more source

A multi-model ensemble approach for reservoir dissolved oxygen forecasting based on feature screening and machine learning

open access: yesEcological Indicators
Dissolved oxygen (DO) concentration in aquatic systems plays a vital role in water aquaculture. An innovative approach that combines feature selection and ensemble learning to predict DO in aquatic ecosystems was proposed.
Peng Zhang   +6 more
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

open access: yesFEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan   +11 more
wiley   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

open access: yesFEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy