Results 71 to 80 of about 40,095 (264)

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Impact of Three Gorges Project Impoundment on Spatiotemporal Variation of Pollutant Flux in Mainstream Yangtze River [PDF]

长江科学院院报
[Objective] To investigate the variation patterns of pollutant fluxes in the Yangtze River mainstream before and after the operation of the Three Gorges Project, this study analyzes the annual variations in water quality, runoff, and pollutant fluxes at ...
PENG Lian, ZHAO Min, QIAN Bao, ZHOU Bing-yi
doaj   +1 more source

The role and interplay of institutions in water governance in the Central Rift Valley of Ethiopia. [PDF]

F1000Res, 2023
Jibat E, Senbeta F, Zeleke T, Hagos F.
europepmc   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source

Construction and application of a real-time irrigation decision system based on the multiple sources data assimilation and weather forecasts

Agricultural Water Management
Improving irrigation strategies is essential for increasing irrigation water productivity (IWP) while maintaining crop yield. We developed a real-time irrigation decision system that couples the soil-water-atmosphere-plant (SWAP) crop simulation model ...
Boyan Sun, Zheng Guo, Taiyu He, Yimin Ding, Lei Zhu, Yuanyuan Zha   +5 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Adaptive Water Management: On the Need for Using the Post-WWII Science in Water Governance. [PDF]

Water Resour Manag (Dordr), 2023
Hjorth P, Madani K.
europepmc   +1 more source

Caring for Groundwater: How Care Can Expand and Transform Groundwater Governance

International Journal of the Commons
Efforts to measure and regulate groundwaters and irrigators are notoriously ineffective. The starting point of this article, therefore, is to question the continued faith in techno-managerial solutions to groundwater depletion.
Margreet Zwarteveen, Carolina Domínguez-Guzmán, Marcel Kuper, Amine Saidani, Jeltsje Kemerink-Seyoum, Frances Cleaver, Himanshu Kulkarni, Lisa Bossenbroek, Hind Ftouhi, Andres Verzijl, Uma Aslekar, Zakaria Kadiri, Tavengwa Chitata, Irene Leonardelli, Seema Kulkarni, Sneha Bhat   +15 more
doaj   +1 more source

Reflecting on twenty years of international agreements concerning water governance: insights and key learning. [PDF]

Int Environ Agreem, 2022
Mirumachi N, Hurlbert M.
europepmc   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source