Results 51 to 60 of about 239,760 (307)

Thermocapillary actuation of droplets on chemically patterned surfaces by programmable microheater arrays [PDF]

open access: yes, 2003
We have designed a microfluidic device for the actuation of liquid droplets or continuous streams on a solid surface by means of integrated microheater arrays.
Darhuber, Anton A.   +3 more
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Measurement of sap flow dynamics through the tomato peduncle using a non-invasive sensor based on the heat field deformation method [PDF]

open access: yes, 2013
Recent contradicting evidence on the contributions of xylem and phloem to tomato fruit growth highlights the need for a more thorough insight into the dynamics of sap flow through the tomato peduncle. In fact, knowledge on sap flow dynamics through small
De Swaef, Tom   +3 more
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Langage articulé par le chauffe-eau dans La Carte et le territoire : entre l’étrangeté et l’intimité

open access: yesRelief: Revue Électronique de Littérature Francaise, 2018
La dizaine d’apparitions du chauffe-eau dans La Carte et le territoire ne semble pas anodine. En contextualisant cette machine sous la plume de Houellebecq, le présent article se propose d’interpréter les liens entre le chauffe-eau et le style de l ...
Hua Hu
doaj   +5 more sources

Optimization of aero-engine condition monitoring by autoregressive model analysis based on wireless communication

open access: yesMeasurement + Control
The high value of aero-engines makes it necessary to extend their life in terms of econ-omy of use. Health management is an important basis for this work.
Mai Xin, Zhifeng Ye, Xing Liu, Xiong Pan
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Experimental study of an instantaneous-heating air source heat pump water heater with a temperature stratified water tank

open access: yesAdvances in Mechanical Engineering, 2016
An instantaneous-heating air source heat pump water heater with a temperature stratified water tank was put forward. The instantaneous-heating air source heat pump water heater was designed to produce hot water instantly by three modes, namely condenser ...
Mingjing Lei   +3 more
doaj   +1 more source

Legionella Infection Risk from Domestic Hot Water

open access: yesEmerging Infectious Diseases, 2004
We investigated Legionella and Pseudomonas contamination of hot water in a cross-sectional multicentric survey in Italy. Chemical parameters (hardness, free chlorine, and trace elements) were determined. Legionella spp.
Paola Borella   +17 more
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

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