Results 51 to 60 of about 5,028,148 (268)

Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani   +10 more
wiley   +1 more source

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni   +19 more
wiley   +1 more source

Effect of Electrolyte Concentration on Bubble Size and Gas-Liquid Interfacial Area in Bubble Column

open access: yesTikrit Journal of Engineering Sciences, 2005
The optimum conditions of bubble column would be the ones that enhance mass transfer and this is accomplished by maximizing gas-liquid interfacial area. In the present work the effect of electrolyte concentration (aqueous solution of sodium chloride NaCl
Farah T. Jassem
doaj   +1 more source

Identification of Gas-Water Two-Phase Flow Patterns in Horizontal Wells of Shale Gas Reservoirs Based on Production Logging Data

open access: yesGeofluids, 2023
In order to clarify the gas-water two-phase flow law in horizontal wells and study the gas-water two-phase flow characteristics in horizontal wells, firstly, the gas-water two-phase in a horizontal well is numerically simulated and analyzed, and the flow
Xiaoyun Zhao   +3 more
doaj   +1 more source

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin   +11 more
wiley   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Holdup, Search and Inefficiency [PDF]

open access: yes
This paper investigates the holdup problem in the dynamic search market where buyers and sellers search for their trading partners and specific investments are made after match but before trade.
Shingo Ishiguro
core  

A method and device for online magnetic resonance multiphase flow detection

open access: yesPetroleum Exploration and Development, 2020
Most multiphase flow separation detection methods used commonly in oilfields are low in efficiency and accuracy, and have data delay. An online multiphase flow detection method is proposed based on magnetic resonance technology, and its supporting device
Feng DENG   +11 more
doaj   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

Data-Driven Gas Holdup Correlation in Bubble Column Reactors Considering Alcohol Concentration and Carbon Number

open access: yesChemEngineering
Due to the complex relationship between various parameters affecting gas holdup in bubble column reactors, a unique correlation for gas holdup does not exist.
Salar Helchi   +4 more
doaj   +1 more source

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