Results 41 to 50 of about 1,520,802 (301)

Tick Sweats [PDF]

open access: yes, 2018
Ticks are obligatory ectoparasites of many vertebrate hosts including human. Osmoregulatory functions of ticks are crucial for the survival, especially, in the off-host ticks in arid area.
Arnsperger, Alyssa   +2 more
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Effects of intake and exhaust manifold water injection on combustion and emission characteristics of a DI diesel engine

open access: yesJournal of Thermal Science and Technology, 2017
Water injection is a technique that has been used for decades to control the combustion and emissions in diesel engines. The effects of water injection at the intake and exhaust manifolds on the combustion and emission characteristics of a direct ...
Mohamed FARAG   +3 more
doaj   +1 more source

Experimental Analysis of Water Pressure and Temperature Influence on Atomization and Evolution of a Port Water Injection Spray

open access: yesApplied Sciences, 2021
Port water injection (PWI) is considered one of the most promising technologies to actively control the increased knock tendency of modern gasoline direct injection (GDI) engines, which are rapidly evolving with the adoption of high compression ratios ...
Lucio Postrioti   +2 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Reentry communication by material addition Patent [PDF]

open access: yes, 1966
Reentry communication by injection of water droplets into plasma layer surrounding space ...
Nelson, C. H.
core   +1 more source

Modeling and optimization of production and distribution of drinking water at VMW [PDF]

open access: yes, 2011
We develop and discuss an operational planning model aiming at minimizing production and distribution costs in large drinking water networks containing buffers with free inflow.
B. Ulanicki   +5 more
core   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Geothermal development and the Salton Sea [PDF]

open access: yes, 1976
One of the limiting factors on energy development in the arid American West is the availability of water. Even geothermal development must take into account the hydrologic cycle of the surrounding area.
Goldsmith, Martin
core   +1 more source

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