Results 51 to 60 of about 6,484,050 (283)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

FACTIBILIDAD EXPERIMENTAL DE LA INYECCIÓN DE AGUA EN LAS ARENAS MUGROSA DEL CAMPO LISAMA

open access: yesRevista Fuentes El Reventón Energético, 2010
Lisama field is located in Magdalena Middle Valley basin and although it was discovered in 1967, its recovery factor does not exceed 14% and its production is declining.
Carlos Eduardo Naranjo Suárez   +2 more
doaj  

Water injection performance and incremental oil recovery in the Lower Kura Depression: a case study of the Mishovdag field

open access: yesИзвестия Томского политехнического университета: Инжиниринг георесурсов
Relevance. This study investigates the potential for incremental oil recovery through water injection in selected wells in the Lower Kura Depression (in the case of Mishovdag field).
Shura Ali Ganbarova
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Detection of effects of rock burst prevention by water injection into coal seam using charge induction method

open access: yesYantu gongcheng xuebao, 2019
For detecting the effects of rock burst prevention by water injection into coal seam using the charge induction method, an experimental method is adopted to study the charge laws during the destruction process of coal samples with different moisture ...
WANG Gang 1, PAN Yi-shan 1, 2, XIAO Xiao-chun 1
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Simulation and Experimental Studies of Mineral Scale Formation Effects on Performance of Sirri-C Oil Field under Water Injection [PDF]

open access: yesIranian Journal of Chemistry & Chemical Engineering, 2011
Water injection is an enhanced oil recovery method which is applied for number of reservoirs especially in the offshore fields around the world. Sea-water injection process is usually associated with important concerns affecting the efficiency, safety ...
Amir Taheri   +5 more
doaj  

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

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