Results 31 to 40 of about 15,780,718 (239)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Agricultural Water ManagementProcess-based simulations, recent observations, and external forcing may contain overlapping information for soil-water estimation, making the incremental value of process-model states difficult to establish.
Quanru Liu +10 more
doaj +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Frontiers in Plant Science, 2020 The growth rate hypothesis (GRH) states that a negative correlation exists between the growth rate and N:P and C:P ratios, because fast-growing organisms need relatively more phosphorus-rich RNA to support their high rates of protein synthesis.
Cong Hu +11 more
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Journal of Rock Mechanics and Geotechnical EngineeringWith the rapid development of nuclear energy, the safe disposal of high-level radioactive waste (HLW) has emerged as a global challenge. Beishan underground research laboratory (URL) is the first underground facility for the development of China's HLW ...
Haoyu Mao +7 more
doaj +1 more source
Stage Monitoring in Turbid Reservoirs with an Inclined Terrestrial Near-Infrared Lidar
Remote Sensing, 2016 To monitor the stage in turbid reservoirs with a sloping bank, it has been proposed to install a near-infrared Lidar on the bank and to orient it so that it points at the water surface with a large incidence angle (between ≈ 30° and 70°).
Serge Tamari +4 more
doaj +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Assessment of daily altimeter-based open ocean water level with hindcast and forecast efficiency
Frontiers in Marine ScienceSatellite altimetry water level measurements are valuable in episodic and climate change related hydrodynamic impact studies, despite their sparse temporal distribution over the global ocean.
Evangelos Voukouvalas +5 more
doaj +1 more source