Results 51 to 60 of about 6,679,528 (309)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Effect of water regime on poplar cultivation [PDF]
Glasnik Šumarskog Fakulteta: Univerzitet u Beogradu, 2006 The effect of water regime on the growth and development of plantations of hydrologically conditioned species, poplars was researched in the alluvial plain of the river Tamiš. The investigations were carried out during the period 2000-2003 on the area of
Letić Ljubomir +2 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Stage–discharge relationship for a pipe overflow structure in both free and submerged flow
Engineering Applications of Computational Fluid Mechanics, 2016 Many facilities for urban drainage systems are equipped with a pipe overflow structure that can often be treated as a circular broad-crested weir. Thus it is possible to evaluate the overflow discharge through this device by measuring the water levels in
Gilles Isenmann +5 more
doaj +1 more source
Model Development and Hindcast Simulations of NOAA’s Gulf of Maine Operational Forecast System
Journal of Marine Science and Engineering, 2016 The National Ocean Service (NOS) of National Oceanic and Atmospheric Administration is developing an operational nowcast/forecast system for the Gulf of Maine (GoMOFS).
Zizang Yang +7 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Effect of active faults in the groundwater level of Shaharchay basin in Urmia [PDF]
تحقیقات کاربردی علوم جغرافیایی, 2017 حذف شدیک جمله Identify water resources management and proper application of relevant officials and managers are the main concern. Groundwater as a most important natural resources of Iran needs to planning and management of all aspects. In this regard, a
Tayebeh Kiani, Zahra Yousefi
doaj
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source