Results 41 to 50 of about 15,780,718 (239)

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Effect of water regime on poplar cultivation [PDF]

Glasnik Šumarskog Fakulteta: Univerzitet u Beogradu, 2006
The effect of water regime on the growth and development of plantations of hydrologically conditioned species, poplars was researched in the alluvial plain of the river Tamiš. The investigations were carried out during the period 2000-2003 on the area of
Letić Ljubomir, Ivanišević Petar, Rončević Savo   +2 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Stage–discharge relationship for a pipe overflow structure in both free and submerged flow

Engineering Applications of Computational Fluid Mechanics, 2016
Many facilities for urban drainage systems are equipped with a pipe overflow structure that can often be treated as a circular broad-crested weir. Thus it is possible to evaluate the overflow discharge through this device by measuring the water levels in
Gilles Isenmann, Salma Bellahcen, José Vazquez, Matthieu Dufresne, Claude Joannis, Robert Mose   +5 more
doaj   +1 more source

Model Development and Hindcast Simulations of NOAA’s Gulf of Maine Operational Forecast System

Journal of Marine Science and Engineering, 2016
The National Ocean Service (NOS) of National Oceanic and Atmospheric Administration is developing an operational nowcast/forecast system for the Gulf of Maine (GoMOFS).
Zizang Yang, Philip Richardson, Yi Chen, John G. W. Kelley, Edward Myers, Frank Aikman, Machuan Peng, Aijun Zhang   +7 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Effect of active faults in the groundwater level of Shaharchay basin in Urmia [PDF]

تحقیقات کاربردی علوم جغرافیایی, 2017
حذف شدیک جمله Identify water resources management and proper application of relevant officials and managers are the main concern. Groundwater as a most important natural resources of Iran needs to planning and management of all aspects. In this regard, a
Tayebeh Kiani, Zahra Yousefi
doaj  

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Water potential in cape gooseberry (Physalis peruviana L.) plants subjected to different irrigation treatments and doses of calcium

Agronomía Colombiana, 2019
To determine whether the management of irrigation and nutrition in cape gooseberry crops with calcium to reduce the cracking of fruits affects the water potential of the plants, the present study was carried out using a randomized block design with 12 ...
Javier Álvarez-Herrera, Hernán González, Gerhard Fischer   +2 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source