Results 71 to 80 of about 6,679,528 (309)
Remote Sensing, 2020 With new Ice, Cloud, and land Elevation Satellite (ICESat)-2 lidar (Light detection and ranging) datasets and classical Landsat imagery, a method was proposed to monitor annual changes of lake water levels and volumes for 35 years dated back to 1980s ...
Nan Xu +5 more
doaj +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Limnological record inferred from diatoms in sediments of Lake Skaliska (north-eastern Poland)
Acta Palaeobotanica, 2013 Subfossil diatoms analysis was employed to reconstruct past environmental changes in Lake Skaliska. This lake, presently a palaeolake, is located on a wide plain called the Skaliska Basin (northern part of Mazury Lake District, north-eastern Poland ...
Sienkiewicz Elwira
doaj +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
The Catastrophic Water Loss of Ancient Lake Prespa: A Chronicle of a Death Foretold
HydrologyThe Prespa–Ohrid lake system in the southwest Balkan region is the oldest permanent lake system in Europe and a global hotspot of biodiversity and endemism.
Dejan Trajkovski, Nadezda Apostolova
doaj +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
GeographiesThis study investigated the hydrogeological characteristics and groundwater dynamics in the shallow aquifer zones of inner Guwahati city, Assam, India. Sixteen dug wells spread across the city, specifically used for domestic purposes, were selected for ...
Smitakshi Medhi +3 more
doaj +1 more source
Knowledge and Management of Aquatic Ecosystems, 2009 Physico-chemical factors and zooplankton diversity were investigated over a two year period in three regions along the 200 km length of Cross River. The objective of the study was to quantify the relative importance of local environmental conditions and ...
Offem B. O. +3 more
doaj +1 more source
Hydrological Alteration Index as an Indicator of the Calibration Complexity of Water Quantity and Quality Modeling in the Context of Global Change [PDF]
, 2019 Modeling is a useful way to understand human and climate change impacts on the water resources of agricultural watersheds. Calibration and validation methodologies are crucial in forecasting assessments.
Bodoque, José María +12 more
core +6 more sources
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source