Results 91 to 100 of about 2,752,436 (316)

Zooplankton of the channel zone of reservoirs of the arid zone: effects of level regime and meteorological conditions

open access: yesТрансформация экосистем, 2019
In the channel areas of the large Tayshir Reservoir valley, zooplankton is unevenly distributed along the longitudinal profile. The number and biomass of communities increases from the upper to lower rea­ ches. In the Durgun Reservoir, which has features
Аlexander V. Krylov   +3 more
doaj   +1 more source

Texas Water Development Board Report 137 [PDF]

open access: yes, 1971
Report on water level data from observation wells in the Northern Panhandle of Texas and discussion of the available groundwater resources and how irrigation has reduced ...
Wyatt, A. Wayne   +1 more
core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Spaceborne GNSS-R Observation of Global Lake Level: First Results from the TechDemoSat-1 Mission

open access: yesRemote Sensing, 2019
Spaceborne global navigation satellite system reflectometry (GNSS-R) data collected by the UK TechDemoSat-1 (TDS-1) satellite is applied to retrieve global lake levels for the first time.
Liwen Xu   +5 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Experimental and Seepage Analysis of Gabion Retaining Wall Structure for Preventing Overtopping in Reservoir Dams

open access: yesApplied Sciences
Recently, heavy rains caused by climate change have resulted in dam failures due to overtopping. This study presents a design method aiming to prevent overtopping failures by applying gabion retaining walls at the dam crest. Simulations, experiments, and
Dal-Won Lee   +5 more
doaj   +1 more source

Citizen volunteer water monitoring on Smith Lake [PDF]

open access: yes, 2005
Publication includes: Lake Facts and Figures; Long-term Trends in Lake Water Quality; Impacts on the Lake and What's Being Done About It; Trouble Waters; Watershed-level Water Quality Differences; Timeline of AAW (Alabama Water Watch), SLCA (Smith Lake ...
Alabama Water Watch
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

The Wave Amplification Mechanism of Resonant Caisson

open access: yesJournal of Marine Science and Engineering
Previous studies have introduced a resonant caisson designed to enhance wave energy extraction in regions with low wave energy density; however, its operational mechanism remains poorly understood.
Jiawei Hao   +3 more
doaj   +1 more source

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