Results 111 to 120 of about 6,679,528 (309)
Based on the Xiaolangdi North Bank Irrigation Area Project, this study combines numerical simulation and BP neural network methods to investigate the sensitivity of tunnel soil and its parameter inversion under continuous heavy rainfall.
Yongxin Li +4 more
doaj +1 more source
Some considerations on coastal processes relevant to sea level rise [PDF]
The effects of potential sea level rise on the shoreline and shore environment have been briefly examined by considering the interactions between sea level rise and relevant coastal processes.
Dally, William R. +3 more
core
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Ghana Market Assessment: Market-Based Provision of Water at the Community Level [PDF]
This market assessment evaluates the potential for decentralized market-based approaches to sustainable safe water service, focusing on the poor in rural communities and small towns in Ghana that are not supplied or connected by municipal schemes to safe
core
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Mitigating the water footprint of export cut flowers from the Lake Naivasha Basin, Kenya [PDF]
Kenya’s cut-flower industry has been praised as an economic success as it contributed an annual average of US$ 141 million foreign exchange (7% of Kenyan export value) over the period 1996-2005 and about US$ 352 million in 2005 alone.
Hoekstra, A.Y., Mekonnen, M.M.
core +1 more source
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
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openaire +1 more source
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source

