Results 101 to 110 of about 6,679,528 (309)

Household Water Demand Estimation using Micro-Level Data [PDF]

open access: yes
La Reunion Island is facing to specific difficulties in supplying drinking water. In the western part of this french departement drincking water is lacking.
Fabrizio Carlevaro   +3 more
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Impact of Three Gorges Reservoir Operation on Water Level at Jiujiang Station and Poyang Lake in the Yangtze River

open access: yesHydrology
The variation in water level at Jiujiang Station (JJS) directly affects flow exchange between the Yangtze River and the Poyang Lake. Quantitative research on the influencing factors of water level changes at JJS is of great importance for water supply ...
Yun Wang   +4 more
doaj   +1 more source

Sea level variability in South African estuaries

open access: yesSouth African Journal of Science, 2013
Sea level variability in the coastal ocean affects water levels in adjacent estuaries over a wide range of periods and to varying distances landward. An assessment is given here of the responses of a number of South African estuaries, focusing on tidal ...
Eckart H. Schumann
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Monitoring Seasonal Hydrological Dynamics of Minerotrophic Peatlands Using Multi-Date GeoEye-1 Very High Resolution Imagery and Object-Based Classification

open access: yesRemote Sensing, 2012
The La Grande River watershed, located in the James Bay region (54°N, Quebec, Canada), is a major contributor to the production of hydroelectricity in the province. Peatlands cover up to 20% of the terrestrial environment in this region.
Monique Bernier   +2 more
doaj   +1 more source

Assesing the Water Quality Trading Ratio in the North Bosque Watershed as an Alternative of Maintaining Water Quality [PDF]

open access: yes, 2015
Water quality standard is defined by the level of environment absorptive capacity of pollutants. Total Maximum Daily Load (TMDL) is a program to maintain the water quality in the impaired river segments. Using the Soil Water Assessment Tool (SWAT).
Fadhliani, F. (Fadhliani)
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Iodine generator for reclaimed water purification [PDF]

open access: yes, 1977
The system disclosed is for controlling the iodine level in a water supply in a spacecraft. It includes an iodine accumulator which stores crystalline iodine, an electrochemical valve to control the input of iodine to the drinking water and an iodine ...
Powell, J. D.   +2 more
core   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

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