Results 81 to 90 of about 909 (218)

miR-137 Affects Vaginal Lubrication in Female Sexual Dysfunction by Targeting Aquaporin-2

Sexual Medicine, 2018
Introduction: Female sexual dysfunction (FSD) is a common disease with serious potential hazards, but it has not received much attention. The pathogenesis of FSD is urgently needed for the diagnosis and treatment of FSD.
Hepeng Zhang, MD, Tianjiao Liu, MD, Ziyun Zhou, MD, Aixia Zhang, MD, Yuan Zhu, MSc, Jing Zhang, MSc, Lianjun Pan, MD, Jiehua Ma, PhD   +7 more
doaj   +1 more source

Durability of Soft Pneumatic Actuators: A Review and Benchmarking Protocol

Advanced Robotics Research, EarlyView.
Lack of durability is a key challenge hindering the broad scale adoption of soft pneumatic actuators (SPAs) in automation industries. This review provides a comprehensive overview of existing research on SPA durability, introduces a standardized durability benchmarking protocol to consolidate the testing of SPAs, and outlines promising directions for ...
Dickson Chiu Yu Wong, Yucheng Luo, Rob Bernardus Nicolaas Scharff   +2 more
wiley   +1 more source

Intelligent Maintenance Review for Robots: Multimodal Information, Deep Diagnosis and Embodied Artificial Intelligence

Advanced Robotics Research, EarlyView.
This review maps the methods to monitor robots’ health by fusing vibration, sound, control signals, vision, force, and oil information with artificial intelligence. It identifies deep learning, transfer learning, digital twins, and physics‐informed models as key methodological pathways enabling earlier diagnosis, safer human–robot collaboration, and ...
Yuting Qiao, Hongbo Wang, Naipeng Li, Shuo Wang, Yaguo Lei, Tonghai Wu, Junyi Cao   +6 more
wiley   +1 more source

Assessment of a Sustainable Water-based Lubricant for Electric Drivelines : Lubrication and Cooling performance of a Water-based Lubricant

, 2022
In recent years, the impact of humans on the environment has been the subject of much debate. Car companies in particular are among the main actors in this environmental degradation with the polluting aspect of combustion cars. However, in recent years, these companies have started to switch to electric cars in order to reduce their impact on the ...
openaire   +1 more source

Functional Fibers in Soft Robotics: Advances in Material, Structural, and Systemic Tactics

Advanced Robotics Research, EarlyView.
Fiber‐form robotic systems offer a scalable pathway toward embodied intelligence in soft robotics. This review surveys functional fibers as material, structural, and systemic elements, highlighting advances in responsive materials, architectural programing, and fabrication strategies.
Joonhee Won, Jaehyun Jang, Hyeonseo Kim, Inyoung Choi, Steve Park, Seongjun Park   +5 more
wiley   +1 more source

Fluid–Structure Interaction Mechanisms of Layered Thickness Effects on Lubrication Performance and Energy Dissipation in Water-Lubricated Bearings

Lubricants
Traditional single-layer water-lubricated rubber or plastic bearings suffer from water film rupture, excessive frictional losses, and insufficient load-carrying capacity, which limit performance and service life in marine propulsion and ocean engineering.
Lun Wang, Xincong Zhou, Hanhua Zhu, Qipeng Huang, Zhenjiang Zhou, Shaopeng Xing, Xueshen Liu   +6 more
doaj   +1 more source

Mitochondrial Dysfunction Unravels the Potential Molecular Link Between Night Shift Work‐Related Circadian Disruption and Elevated Blood Pressure in Human and Mouse Models

Advanced Science, EarlyView.
This diagram illustrates that night shift work disrupts circadian clock genes (like CLOCK, BMAL1) in both humans and mice. This disruption leads to mitochondrial dysfunction (imbalanced fusion/fission proteins) and increased oxidative stress, which is identified as the primary mechanism ultimately causing elevated blood pressure.
Zhaoqiang Jiang, Yifan Dou, Yingnan Lei, Shuang Liu, Jialin Zhou, Jiaping Li, Huadong Xu, Lingfang Feng, Yongxin Li, Chuyan Zhang, Tao Li, Jianfei Wang, Xing Zhang, Xinran Wang, Luyao Liu, Jingjing Zhang, Jianlin Lou   +16 more
wiley   +1 more source

Remote Magnetomechanical Neuromodulation Uncovers Therapeutic Mechanisms for Alleviating Parkinsonian Symptoms in Freely Moving Mice

Advanced Science, EarlyView.
Magnetomechanical neuromodulation using magnetic nanodiscs enables remote activation of neurons. In a hemiparkinsonian mouse model, alternating magnetic fields actuate the nanodiscs to generate torque that opens mechanosensitive ion channels within the subthalamic nucleus, thereby modulating basal ganglia motor circuitry.
Anouk Wolters, Lorenzo Signorelli, Christian Herff, Sophia Gimple, Renzo Riemens, Gunter Kenis, Kim Rijkers, Hamed Shabani, Jyh‐Jang Sun, Yasin Temel, Hans Clusmann, Danijela Gregurec, Sarah‐Anna Hescham   +12 more
wiley   +1 more source

In Situ Stress‐Dispersing Hydrogel Millispheres via Load Redistribution to Restore Nucleus Pulposus Metabolic Homeostasis

Advanced Science, EarlyView.
Local stress concentration disrupts metabolic homeostasis and induces inflammation in the nucleus pulposus (NP), thereby accelerating intervertebral disc degeneration (IDD). A biomimetic HA/ChS hydrogel millimeter sphere (ChS@HM) is developed to enable synergistic stress dispersion and sustained hydration lubrication.
Ang Li, Hui Yuan, Honglei Xiao, Xiaodong Liu, Wenguo Cui   +4 more
wiley   +1 more source

NMI Regulates Adipose Adaptive Thermogenesis Through TLR4/IRF3 Signaling to Promote Obesity

Advanced Science, EarlyView.
Adipose tissue‐derived NMI is secreted under metabolic stress and suppresses adaptive thermogenesis through TLR4/IRF3 signaling, repressing the PPARα/PGC‐1α/UCP1 thermogenic transcriptional program. Genetic ablation or anti ‐ NMI monoclonal antibody treatment enhances energy expenditure, protects against DIO, and ameliorates adipose tissue inflammation,
Ting‐Ting Li, Xin‐Yuan Zhao, Min Zhang, Zhuang‐Feng Weng, Xiao‐Ran Guo, Ying‐Fang Liu, Qiao‐Ping Wang, Huan‐Huan Liang   +7 more
wiley   +1 more source