Results 31 to 40 of about 3,719,932 (269)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Effect of irrigation network rehabilitation on water management-case study: Tanta Navigation canal – Egypt

Alexandria Engineering Journal, 2019
Tanta Navigation canal is a 38.0 km long main canal serving 65,000 ha. in the Nile Middle Delta of Egypt. The main branch of Tanta canal is El-Kased canal with 34.0 km long, and serving 60% of Tanta Canal served area.The main problem was the inability to
Talaat ElGamal, Mohamed ElFetyany, Gamal ElKassar   +2 more
doaj   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Insight for sustainable supplemental irrigation development for Cocoa in changing Ghana’s agroforestry landscapes

Discover Sustainability
Cocoa production in Ghana faces challenges from climate change and land use dynamics, necessitating sustainable intensification through supplemental irrigation.
Seifu A. Tilahun, Andoh K. Amponsah, Gerald Atampugre, Birhanu Z. Birhanu, Moctar Dembélé, Sylvester Darko, Tafadzwanashe Mabhaudhi, Olufunke Cofie   +7 more
doaj   +1 more source

Security in flexibility: accessing land and water for irrigation in Kenya’s changing rural environment

Cahiers Agricultures, 2022
In the semi-arid lands of southern Kenya, a dynamic process of farmer-led irrigation has developed over the past two decades. It is characterised by short-term agreements to access land and water. Resident and migrant farmers, capital providers and local
Duker Annelieke E.C., Karimba Benson Mutuma, Wani Grace E., Prasad Pooja, Van der Zaag Pieter, De Fraiture Charlotte   +5 more
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Exploring the smallholder irrigation equipment supply landscape in Zambia: a scoping review

Discover Sustainability
Limited irrigation adoption hinders agricultural production for Zambia's smallholder farmers, despite its potential to mitigate the impact of erratic rainfall patterns. This scoping review investigates the irrigation equipment supply landscape in Zambia,
Dennis Junior Choruma, Tinashe Lindel Dirwai, Greenwell Matchaya, Winnie Kasoma-Pele, Munyaradzi Mutenje   +4 more
doaj   +1 more source

Early transplanting of rainfed rice minimizes irrigation demand by utilizing rainfall

Environmental Systems Research, 2021
Background Rainfall is the key contributor to provide soil moisture for wet season rice (T. Aman) cultivation. Erratic rainfall often causes water shortage resulting negative impact on plant growth and grain yield.
Md. Belal Hossain, Debjit Roy, Mir Nurul Hasan Mahmud, Priya Lal Chandra Paul, Mst. Shetara Yesmin, Palash Kumar Kundu   +5 more
doaj   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source