Results 41 to 50 of about 3,719,932 (269)
Water marketing effects on crop-water management
This study considers a water marketing system in which farmers can buy a given amount of water, at a fixed price, and sell the amount not used. The system could induce farmers to upgrade their irrigation systems and reduce water application and drainage ...
J Letey, A Dinar
doaj
Income growth, population and savings in the Southern Africa Development Community region
Background: The Southern Africa Development Community (SADC) faces pervasive income stagnation, high inequality, increasing population growth rates and poverty.
Greenwell Matchaya +2 more
doaj +1 more source
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
If adequate water supplies are to be continually available, and if Periods Of drought are to be dealt with effectively, management of ground water is essential on every farm and in every city county, water district, and region using ground-water ...
V Scott, J Scalmanini
doaj
Sample size requirements for riverbank macrolitter characterization
Anthropogenic litter is omnipresent in terrestrial and freshwater systems, and can have major economic and ecological impacts. Monitoring and modeling of anthropogenic litter comes with large uncertainties due to the wide variety of litter ...
Sjoukje I. de Lange +14 more
doaj +1 more source
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
A study was conducted to evaluate the quality of groundwater in Barishal district of Bangladesh for both irrigation and drinking purposes. Sixty water samples were collected and analyzed in the Biochemistry laboratory of Bangladesh Agricultural ...
Gulshan Yasmin +4 more
doaj +1 more source
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source

