Results 61 to 70 of about 687,649 (293)

Gas dynamics of the central few parsec region of NGC 1068 fuelled by the evolving nuclear star cluster [PDF]

open access: yes, 2010
High resolution observations with the NIR adaptive optics integral field spectrograph SINFONI at the VLT proved the existence of massive and young nuclear star clusters in the centres of a sample of Seyfert galaxies.
A. Burkert   +72 more
core   +3 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Sensitivity of fish diel vertical migration depths to future changes in the Pacific Ocean oxygen minimum zone

open access: yesFrontiers in Marine Science
Diel vertical migrations in the ocean play a key role in predator-prey dynamics and the functioning of the biological carbon pump. However, changes in ocean conditions including warming and deoxygenation threaten to significantly perturb vertical ...
Sam Ditkovsky   +6 more
doaj   +1 more source

Atmospheric controlled freshwater release at the Laptev Sea continental margin [PDF]

open access: yesPolar Research, 2011
Considerable interannual differences were observed in river water and sea-ice meltwater inventory values derived from δ18O and salinity data in the Eurasian Basin along the continental margin of the Laptev Sea in the summers of 1993 and 1995, and ...
Dorothea Bauch   +7 more
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Characterization of the spawning area of tuna species on the northern Tunisian coasts

open access: yesScientia Marina, 2016
Early life stages of tuna species were investigated along the northern coasts of Tunisia in the summer of 2010, from 7 to 14 July. A total of 74 stations, distributed on a regular grid, were sampled.
Wael Koched   +3 more
doaj   +1 more source

Unnamed locations, underspecified regions, and other linguistic phenomena in geographic annotation of water-based locations [PDF]

open access: yes, 2010
This short paper investigates how locations in or close to water masses in topics and documents (e.g. rivers, seas, oceans) are referred to. For this study, 13 topics from the GeoCLEF topics 2005-2008 aiming at documents on rivers, oceans, or sea ...
Leveling, Johannes
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Hydrography at the North Mouth of La Paz Bay, Baja California Sur, Mexico

open access: yesCiencias Marinas, 2007
To describe the hydrographical variability at the North Mouth of La Paz Bay, its main point of communication with the Gulf of California, CTD data were analyzed from four sampling surveys conducted during an annual cycle (May, July and October 2001, and
M Obeso-Nieblas   +5 more
doaj   +1 more source

Formation and Structure of Low Density Exo-Neptunes

open access: yes, 2011
Kepler has found hundreds of Neptune-size (2-6 R_Earth) planet candidates within 0.5 AU of their stars. The nature of the vast majority of these planets is not known because their masses have not been measured.
Borucki   +31 more
core   +1 more source

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