Results 61 to 70 of about 151,095 (259)
Sensitivity of Antarctic Bottom Water Formation and Export to Horizontal Model Resolution
Journal of Advances in Modeling Earth SystemsThe formation of Antarctic Bottom Water (AABW) is a key process in the global ocean circulation, but modeling the formation and downslope flow of AABW represents an ongoing challenge for ocean and climate models due to the high horizontal resolution ...
Christina Schmidt +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Український антарктичний журнал, 2019 Aim of works is implementation of duties, taken by Ukraine on XXXVI Commission for the Conservation of Antarctic Marine Living Resources (CCAMLR) Session and study of habitation of main fishing objects in Antarctica waters.
V. V. Paramonov
doaj +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline
FEBS Open Bio, EarlyView.Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey +4 more
wiley +1 more source
Water Mass Archaeology: Tracing water masses to the surface
WP5 investigates how ice sheet meltwater discharge affects deep water formation, pole-to-pole connections, and large-scale ocean circulation, including the AMOC and ACC. It combines new ocean observations, innovative analyses, and modelling approaches to better understand how freshwater influences the global climate system.
openaire +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
FEBS Open Bio, EarlyView.RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
Scientia Marina, 2001 CTD sections carried out in September 1998 are used to describe the water masses, geostrophic circulation and mass transport in the easternmost branch of the Canary Current. The surface water mass (< 600 m) consists of North Atlantic Central Water (NACW)
Alonso Hernández-Guerra +4 more
doaj +1 more source
Injection of Oxygenated Persian Gulf Water Into the Southern Bay of Bengal
Geophysical Research Letters, 2020 Persian Gulf Water (PGW) is an oxygenated, high‐salinity water mass that has recently been detected in the Bay of Bengal (BoB). However, little is known about the transport pathways of PGW into the BoB.
Peter M. F. Sheehan +5 more
doaj +1 more source