Results 81 to 90 of about 151,095 (259)

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Recent changes in the upper oceanic water masses over the Indian Ocean using Argo data. [PDF]

Sci Rep, 2023
Shee A, Sil S, Gangopadhyay A.
europepmc   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

The influence of waves and bubbles on oxygen in the ocean interior

Environmental Research Letters
Bubble-mediated exchange during wave breaking is an essential pathway for oxygen transfer at the ocean–atmosphere interface. Conventional wind-dependent gas transfer velocity formulations generally ignore wave-bubble effects and use local wind speed ...
Paridhi Rustogi, Laure Resplandy, Seth Bushinsky, Luc Deike   +3 more
doaj   +1 more source

Transformation of South Pacific Water Masses in the Halmahera Sea [PDF]

BIO Web of Conferences
The Halmahera Sea is part of the eastern entry route of the Indonesian throughflow (ITF) passages. The characteristics and transformation of the South Pacific water masses are presented based on the HYCOM model (Hybrid Coordinate Ocean Model) and direct ...
Prasetyo Wahyudi, Wicaksono Ashari, Purwandana Adi, Edikusmanto, Surinati Dewi, Zheng Wang   +5 more
doaj   +1 more source

Water masses shape pico-nano eukaryotic communities of the Weddell Sea. [PDF]

Commun Biol, 2023
Flegontova O, Flegontov P, Jachníková N, Lukeš J, Horák A.   +4 more
europepmc   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Glacial Expansion of Deoxygenation in the Arabian Sea

Geophysical Research Letters
The mechanisms by which ongoing climate change influences ocean Oxygen Minimum Zones (OMZs) are insufficiently understood, making it essential to examine their long‐term variations under substantial climatic forcing.
Deepak Kumar Rai, Jitender Kumar, Abul Qasim, Sanjeev Kumar, Ravi Bhushan, Kaustubh Thirumalai, Arvind Singh   +6 more
doaj   +1 more source

Changes in hydrodynamics and nutrient load of the coastal bay induced by Typhoon Talim (2023)

Frontiers in Marine Science
Typhoons can greatly alter the hydrodynamic and nutrient supply in coastal oceans. However, due to the complex conditions of typhoons, such as their intensity, even slight changes may cause substantial changes in hydrodynamics and nutrient supply, which ...
Chunqing Chen, Chunqing Chen, Qibin Lao, Qibin Lao, Xin Zhou, Qingmei Zhu, Qingmei Zhu, Fajin Chen, Fajin Chen, Fajin Chen   +9 more
doaj   +1 more source

Vertical redistribution of principle water masses on the Northeast Greenland Shelf. [PDF]

Nat Commun, 2022
Gjelstrup CVB, Sejr MK, de Steur L, Christiansen JS, Granskog MA, Koch BP, Møller EF, Winding MHS, Stedmon CA.   +8 more
europepmc   +1 more source