Results 51 to 60 of about 208,595 (265)

Water striders adjust leg movement speed to optimize takeoff velocity for their morphology

open access: yesNature Communications, 2016
How water striders escape from danger by jumping vertically from the water surface without sinking is an open question in biomechanics. Yanget al. show that water strider species with varying leg lengths and body masses tune their leg movements to ...
Eunjin Yang   +4 more
doaj   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

The Italian water movement and the politics of the commons

open access: yesWater Alternatives, 2016
The article contributes to the debate on the commons as a political strategy to counter the privatisation of water services by focusing on the experience of the Italian water movement.
Chiara Carrozza , Emanuele Fantini
doaj  

Horizontal and vertical movements of the common dolphinfish (Coryphaena hippurus) in La Paz Bay, Mexico

open access: yesCiencias Marinas, 2015
The common dolphinfish (Coryphaena hippurus) is an important resource for the sport-fishing industry in Mexico. It is captured incidentally by the eastern Pacific purse-seine tuna fishery and in coastal areas by artisanal fisheries.
Cristina Hernández-Tlapale   +3 more
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Movements on Water Surfaces [PDF]

open access: yesNature, 1914
MR. MARTIN'S second question is more easily answered than his first. The surface tension of clean water is about three times as great as that of water containing soap, so when the soap touches the wet surface the surrounding wet being no longer pulled towards the soap as strongly as it is pulled away, obeys the latter force as fast as it can.
openaire   +5 more sources

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

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