Results 71 to 80 of about 201,786 (264)

Variability in nomadism: environmental gradients modulate the movement behaviors of dryland ungulates

Ecosphere, 2019
Studying nomadic animal movement across species and ecosystems is essential for better understanding variability in nomadism. In arid environments, unpredictable changes in water and forage resources are known drivers of nomadic movements.
Dejid Nandintsetseg, Chloe Bracis, Peter Leimgruber, Petra Kaczensky, Bayarbaatar Buuveibaatar, Badamjav Lkhagvasuren, Buyanaa Chimeddorj, Shiilegdamba Enkhtuvshin, Ned Horning, Takehiko Y. Ito, Kirk Olson, John Payne, Chris Walzer, Masato Shinoda, Jared Stabach, Melissa Songer, Thomas Mueller   +16 more
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Water community networks and the appropriation of neoliberal practices: social technology, depoliticization, and resistance

Ecology and Society, 2019
In the 1990s, various attempts to privatize water services in Latin America came from international financial institutions. Several social movements emerged to protest against privatization, especially from community and indigenous organizations ...
Emilie Dupuits
doaj   +1 more source

Investigating water movements around a shallow shipwreck in Big Tub Harbour of Lake Huron: Implications for managing and preserving underwater shipwrecks. [PDF]

PLoS One, 2023
Flood B, Girihagama L, Wells MG, Valipour R, Semcesen P, Parker S.   +5 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Concerted conformational dynamics and water movements in the ghrelin G protein-coupled receptor. [PDF]

Elife, 2021
Louet M, Casiraghi M, Damian M, Costa MG, Renault P, Gomes AA, Batista PR, M'Kadmi C, Mary S, Cantel S, Denoyelle S, Ben Haj Salah K, Perahia D, Bisch PM, Fehrentz JA, Catoire LJ, Floquet N, Banères JL.   +17 more
europepmc   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Water movement in porous materials: Part 2 - The separation of the components of water movement

British Journal of Applied Physics, 1963
Vapour conductivities kv estimated from hydrogen diffusion in porous solids of decreasing moisture content theta rise slowly from zero at saturation θT to a maximum near dryness, and then fall rapidly again to zero at complete dryness. Liquid conductivities kl, computed from pore size distributions, and estimated from previous water transport ...
openaire   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source