Results 61 to 70 of about 208,595 (265)
Lakes, ponds, reservoirs, and flowing waters are dynamic systems in which organisms live and grow and diverse biogeochemical reactions occur. Through theory, experimentation, in the laboratory and in the field, and modeling, the mechanisms influencing the flow of water have been identified and evaluated.
Hamilton, David, MacIntyre, Sally
openaire +2 more sources
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Ciencias Marinas, 1993 Horizontal and vertical movements are described for four scalloped hammerhead sharks (Sphyrna lewini) tagged with ultrasonic transmitters. The trackings were carried out during August 1986, 1988-1989, and July 1989 in the pelagic environment surrounding
AP Klimley +2 more
doaj +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Applied SciencesThe study of formation pressure holds great significance for both exploration and development. The formation pressure coefficient is a crucial parameter in geology, encompassing various aspects.
Xiaoping Mao +6 more
doaj +1 more source
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
The Application of Piezoelectric Sensor as Energy Harvester from Small-scale Hydropower
E3S Web of Conferences, 2018 Renewable energy technology nowadays is advancing in research and application as an alternative for non-renewable energy sources including fossil fuels and coals since it is considerably less hazardous for the environment.
Zakaria Hidayatul Aini, Loon Chan Men
doaj +1 more source
Movement of Water in Glaciers [PDF]
Journal of Glaciology, 1972 AbstractA network of passages situated along three-grain intersections enables water to percolate through temperate glacier ice. The deformability of the ice allows the passages to expand and contract in response to changes in pressure, and melting of the passage walls by heat generated by viscous dissipation and carried by above-freezing water causes ...
openaire +1 more source
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
Ecosphere, 2019 Studying nomadic animal movement across species and ecosystems is essential for better understanding variability in nomadism. In arid environments, unpredictable changes in water and forage resources are known drivers of nomadic movements.
Dejid Nandintsetseg +16 more
doaj +1 more source