Results 61 to 70 of about 220,405 (309)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The persistent water problems of Lima, Peru:Neoliberalism, institutional failures and social inequalities

open access: yes, 2012
The contingent relation between water governance and nature neoliberalization has defined most interventions in the water sector around the world in recent years. In the case of the Peruvian capital Lima, the provision of water and sanitation services in
Ioris, A.A.
core   +1 more source

Water striders adjust leg movement speed to optimize takeoff velocity for their morphology

open access: yesNature Communications, 2016
How water striders escape from danger by jumping vertically from the water surface without sinking is an open question in biomechanics. Yanget al. show that water strider species with varying leg lengths and body masses tune their leg movements to ...
Eunjin Yang   +4 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

The Italian water movement and the politics of the commons

open access: yesWater Alternatives, 2016
The article contributes to the debate on the commons as a political strategy to counter the privatisation of water services by focusing on the experience of the Italian water movement.
Chiara Carrozza , Emanuele Fantini
doaj  

Multi-Source Glacial Lake Outburst Flood Hazard Assessment and Mapping for Huaraz, Cordillera Blanca, Peru

open access: yesFrontiers in Earth Science, 2018
The Quillcay catchment in the Cordillera Blanca, Peru, contains several glacial lakes, including Lakes Palcacocha (with a volume of 17 × 106 m3), Tullparaju (12 × 106 m3), and Cuchillacocha (2 × 106 m3).
Holger Frey   +6 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Horizontal and vertical movements of the common dolphinfish (Coryphaena hippurus) in La Paz Bay, Mexico

open access: yesCiencias Marinas, 2015
The common dolphinfish (Coryphaena hippurus) is an important resource for the sport-fishing industry in Mexico. It is captured incidentally by the eastern Pacific purse-seine tuna fishery and in coastal areas by artisanal fisheries.
Cristina Hernández-Tlapale   +3 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Social media activism : water as a common good [PDF]

open access: yes, 2018
Published: 27 February 2019This book focuses on the referendums against water privatization in Italy and explores how activists took to social media, ultimately convincing twenty-seven million citizens to vote.
CERNISON, Matteo
core   +1 more source

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