Results 71 to 80 of about 1,025,950 (344)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

The Italian water movement and the politics of the commons

open access: yesWater Alternatives, 2016
The article contributes to the debate on the commons as a political strategy to counter the privatisation of water services by focusing on the experience of the Italian water movement.
Chiara Carrozza , Emanuele Fantini
doaj  

Water Movements

open access: yes
Lakes, ponds, reservoirs, and flowing waters are dynamic systems in which organisms live and grow and diverse biogeochemical reactions occur. Through theory, experimentation, in the laboratory and in the field, and modeling, the mechanisms influencing the flow of water have been identified and evaluated.
Hamilton, David, MacIntyre, Sally
openaire   +2 more sources

An Ecological Study of the Lagoons Surrounding the John F. Kennedy Space Center, Brevard County, Florida [PDF]

open access: yes, 1975
The studies reported here are the result of a three year effort to define the major biological, microbiological, chemical and geological characteristics of the water of the Indian River lagoon around the Kennedy Space Center and to determine the ...
Clark, K. B.   +4 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Horizontal and vertical movements of the common dolphinfish (Coryphaena hippurus) in La Paz Bay, Mexico

open access: yesCiencias Marinas, 2015
The common dolphinfish (Coryphaena hippurus) is an important resource for the sport-fishing industry in Mexico. It is captured incidentally by the eastern Pacific purse-seine tuna fishery and in coastal areas by artisanal fisheries.
Cristina Hernández-Tlapale   +3 more
doaj   +1 more source

Spatial heterogeneity and irreversible vegetation change in semi-arid grazing systems [PDF]

open access: yes, 2002
Recent theoretical studies have shown that spatial redistribution of surface water may explain the occurrence of patterns of alternating vegetated and degraded patches in semiarid grasslands.
Andel, J., van   +11 more
core   +2 more sources

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Evaluation of NRA tracking studies. Future projects and technical development [PDF]

open access: yes, 1992
Fish tracking is a valuable technique for the provision of detailed information on the behaviour patterns of individual fish especially during estuarine and riverine migration. 2. Tracking studies help in the provision of a comprehensive description of
Mills, C.P.R.
core  

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

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