Results 81 to 90 of about 1,025,950 (344)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

A Systematic Review of the Health Impacts of Mass Earth Movements (Landslides) [PDF]

, 2015
Background. Mass ground movements (commonly referred to as ‘landslides’) are common natural hazards that can have significant economic, social and health impacts.
Kennedy, Iain, Murray, Virginia, Petley, Dave N., Williams, Richard   +3 more
core   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Horizontal and vertical movements of the scalloped hammerhead shark, Sphyrna lewini, in the southern Gulf Of California, Mexico

Ciencias Marinas, 1993
Horizontal and vertical movements are described for four scalloped hammerhead sharks (Sphyrna lewini) tagged with ultrasonic transmitters. The trackings were carried out during August 1986, 1988-1989, and July 1989 in the pelagic environment surrounding
AP Klimley, I Cabrera-Mancillas, JL Castillo-Geniz   +2 more
doaj   +1 more source

Behavior, neurobiology, and behavioral ecology (session summary; all summaries compiled by R.A. Wahle) [PDF]

, 2018
Published ...
Lavalli, Kari
core   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

The Relationship between the Time Difference of Formation Water Infiltration Rate, Tectonic Movement, and the Formation Pressure Coefficient

Applied Sciences
The study of formation pressure holds great significance for both exploration and development. The formation pressure coefficient is a crucial parameter in geology, encompassing various aspects.
Xiaoping Mao, Shuxian Li, Xiurong Chen, Xuehui Li, Fan Yang, Yuexing Yang, Zhen Li   +6 more
doaj   +1 more source

Modelling Water Erosion and Mass Movements (Wet) by Using GIS-Based Multi-Hazard Susceptibility Assessment Approaches: A Case Study—Kratovska Reka Catchment (North Macedonia) [PDF]

, 2023
Bojana Aleksova, Tin Lukić, Ivica Milevski, Velibor Spalevıć, Slobodan B. Marković   +4 more
openalex   +1 more source

Urban comix: Subcultures, infrastructures and “the right to the city” in Delhi [PDF]

, 2018
This article argues that comics production in India should be configured as a collaborative artistic endeavour that visualizes Delhi’s segregationist infrastructure, claiming a right to the city through the representation and facilitation of more ...
Davies, D.
core   +1 more source