Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis
Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner+7 more
wiley +1 more source
Friction Tubes to Generate Nanobubble Ozone Water with an Increased Half-Life for Virucidal Activity [PDF]
Nanobubbles and related technologies are expected to be highly utilized in water resource-based industries such as water purification, crops, horticulture, medicine, bio, and sterilization. Ozone, a chemical with high sterilizing power, is known as a natural substance that is reduced to oxygen and water after reacting with pollutants.
arxiv
Water management system and an electrolytic cell therefor Patent [PDF]
Description of electrical equipment and system for purification of waste water by producing silver ions for bacterial ...
Albright, C. F., Gillerman, J. B.
core +1 more source
Brucella NyxA and NyxB dimerization enhances effector function during infection
Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre+4 more
wiley +1 more source
Iodine generator for reclaimed water purification [PDF]
The system disclosed is for controlling the iodine level in a water supply in a spacecraft. It includes an iodine accumulator which stores crystalline iodine, an electrochemical valve to control the input of iodine to the drinking water and an iodine ...
Powell, J. D.+2 more
core +1 more source
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg+2 more
wiley +1 more source
Metal-organic frameworks applied for water purification [PDF]
Metal-organic frameworks (MOFs) which are materials constructed from metal ions/clusters bridged with organic linkers have emerged as an important family of porous materials for widely varying applications. The purification of water polluted with both of
Chaemchuen, Somboon+3 more
core +2 more sources
Quick appraisal of "Sistema de suministro desde el embalse del Cenajo a la Mancomunidad de Canales del Taibilla" [PDF]
The project under assessment concerns the construction of an aqueduct in order to divert water from Tajo-Segura Channel onto the Cenajo reservoir and to the water purification plants of Sierra de la Espada and of Campotéjar.
COWI+1 more
core
A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini+11 more
wiley +1 more source
Development and implementation of ozone purification systems for water pipes and wells [PDF]
This paper is dedicated to the study of the importance and efficiency of developing and implementing ozone purification systems for disinfecting drinking water sources, water pipes, and wells.
Kalandarov Palvan+5 more
doaj +1 more source