Results 91 to 100 of about 12,422,346 (309)

Investigating the extent of PFAS contamination in the Upper Danube Basin across environmental compartments

open access: yesEnvironmental Sciences Europe
Background Per- and polyfluoroalkyl substances (PFAS) are emerging organic pollutants widely detected in environmental systems, posing risks to human health and the ecosystem.
Meiqi Liu   +10 more
doaj   +1 more source

Impact of UV–HO Advanced Oxidation and Aging Processes on GAC Capacity for the Removal of Cyanobacterial Taste and Odor Compounds

open access: yesEnvironmental Health Insights, 2015
Cyanobacteria and their taste and odor (T&O) compounds are a growing concern in water sources globally. Geosmin and 2-methylisoborneol (MIB) are the most commonly detected T&O compounds associated with cyanobacterial presence in drinking water sources ...
Arash Zamyadi   +4 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

A novel fabrication method of vertically aligned carbon nanotubes by single-stage floating catalyst CVD

open access: yesBMC Chemistry
The single-stage floating catalyst chemical vapor deposition (SS-FCCVD) method using the ferrocene route (e.g., ferrocene: catalyst and camphor: carbon source) offers significant but largely unexplored versatility for the production of carbon nanotubes ...
B. V.N. Sewwandi   +5 more
doaj   +1 more source

Water quality assessment, trophic classification and water resources management [PDF]

open access: yes, 2010
Quantification of water quality (WQ) is an integral part of scientifically based water resources management. The main objective of this study was comparative analysis of two approaches applied for quantitative assessment of WQ: the trophic level index ...
Gal, Gideon   +4 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Final Report of the Kansas Special Commission on Water Quality Standards [1998]

open access: yes, 1998
"Transmitted on June 30, 1998, to Governor Bill Graves, Kansas House of Representatives, Kansas State Senate."Summary of Preliminary Recommendations -- Background -- Summary of Concerns -- Response to Legislative Questions -- Recommendations and Policy ...
Kansas Special Commission on Water Quality Standards.
core  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Water quality modeling sampling program: areawide waste treatment management plan for the southeast Texas

open access: yes, 1975
18 pgs. and 2 mapsThis report has been prepared in accordance with an agreement between the Texas Water Quality Board and the South East Texas Regional Planning Commission (SETRPC) covering the improvement of steady-state mathematical models of stream ...
Texas Water Quality Board, Administrative Operations Division
core   +1 more source

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