Results 81 to 90 of about 12,422,346 (309)

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

2002 Texas Water Quality Inventory [PDF]

open access: yes, 2002
This fact sheet describes basic attributes of Waller Creek as well as information on historical fish kills and environmental concerns.Waller Creek Working ...
Texas Commission on Environmental Quality
core   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Prepared for Public Meeting, Galveston Bay Enforcement Conference, Houston, Texas

open access: yes, 1972
12 pagesOne result of the Galveston Bay Enforcement Conference was the formation of the Galveston Bay Technical Committee - a committee composed of personnel from the staffs of the Texas Water Quality Board and the EPA.
Texas Water Quality Board
core   +2 more sources

Integrated water quality management for drinking water of good quality

open access: yesWater Science and Technology, 2003
The Nagoya Waterworks and Sewerage Bureau has developed original supporting tools for the systematic and cost-effective management of problem solving. An environmental information map and prediction of pollutant reaching are used for rapid and appropriate proper countermeasures against water quality accidents in the source area.
openaire   +2 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

A multidisciplinary approach for evaluating spatial and temporal variations in water quality

open access: yes, 2019
The primary goal of this study is to investigate the classification capability of several artificial intelligence techniques, including the decision tree (DT), multilayer perceptron (MLP) network, Naïve Bayes, radial basis function (RBF) network, and ...
Dung, Tran Duc   +13 more
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

401 Water quality certification

open access: yes
Water Boards Water Boards KRI STINE MURRAY, CHAIR I JAYNE J o y, EXECUTIVE OFFICER e GAVIN N EWSOM GOVfA NOR YANA GARCIA SECRETARY FOR ENVIRONMENTAL PROTECTION 3737 Main Street, Suite 500, Riverside, CA 92501-3348 I www.waterboards.ca.gov/santaana Santa ...
California Regional Water Quality Control Board;
core   +1 more source

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