Results 101 to 110 of about 18,853,489 (341)
Examining Water Quality along Cozine Creek [PDF]
, 2017 Water is an essential resource for all life. Water sustains ecological processes that are important to the survival of fish, vegetation, wetlands, and birds. It contributes to humans by providing drinking water, irrigation, and also is an inspiration for
Berg, Noah +6 more
core +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Microorganisms, 2020 Keratinases are considerably gaining momentum in green technology because of their endowed robustness and multifaceted application potentials, such as keratinous agro-wastes valorization.
Nonso E. Nnolim +3 more
doaj +1 more source
ECOLOGIC APPROACH TO THE RESTORATION PROCESS AT AREAS DEGRADED BY MINING OPERATIONS [PDF]
, 2018 Donetsk Region belongs to the zone of the most Ukrainian critical ones in provision with water and the quality of water. The main reason of the water quality deterioration is anthropogenic pollution due to untreated water discharge by the region’s ...
Chepak, Olga +2 more
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Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Water Quality Monitoring [PDF]
This activity is designed to study the water quality of a stream in your area, by measuring the temperature, pH, alkalinity, conductivity and total dissolved solids.
Charlotte Naples
core
Agriculture drainage affects river water quality [PDF]
, 2004 The acidic level of the freshwater is a major concern to water treatment plant operators. Extremely acidic freshwater could affect the operation of the treatment plant in many ways.
Hashim, Normala +5 more
core
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source