Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Hydrochemical characteristics and water quality assessment for drinking and agricultural purposes in District Jacobabad, Lower Indus Plain, Pakistan [PDF]
, 2018 Asfandyar Shahab +5 more
openalex +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Factors Affecting Water Quality and the Structure of Zooplankton Communities in Wastewater Reservoirs of the Right-Bank Sorbulak Canal System (South-Eastern Kazakhstan) [PDF]
, 2022 Elena Krupa +2 more
openalex +1 more source
Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
Effect of nutrient ratios of Water Soluble Fertilizers on Quality of Tomato (Solanum lycopersicum L.) under fertigation [PDF]
, 2022 Minnu John +3 more
openalex +1 more source
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Life's a Beach: Using Role-Playing Scenarios to Facilitate Water Quality Studies [PDF]
, 2018 Christie Sampson +2 more
openalex +1 more source
Influence of intensive water management and water quality on recreation and business in tourism [PDF]
, 2022 Zuzana Dvořáková Líšková +4 more
openalex +1 more source