Results 81 to 90 of about 17,487,572 (398)

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

open access: yesFEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer   +7 more
wiley   +1 more source

Preparation and Characterization of Sludge-Based Magnetic Biochar by Pyrolysis for Methylene Blue Removal

open access: yesNanomaterials, 2021
The development of low-cost adsorbent is an urgent need in the field of wastewater treatment. In this study, sludge-based magnetic biochar (SMB) was prepared by pyrolysis of sewage sludge and backwashing iron mud without any chemical agents.
Huiping Zeng   +5 more
doaj   +1 more source

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

open access: yesFEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur   +5 more
wiley   +1 more source

Water Quality Considerations in Rainwater Harvesting Case Study of Heavy Metal Contamination in Kampala City [PDF]

open access: yes, 2018
Past studies have established a link between industrialization and heavy metal contamination of rainwater. However, no such study has been done in Kampala, or elsewhere in Uganda.
Adekhela, M. S. (Mulindi)   +1 more
core   +1 more source

Photosynthesis under far‐red light—evolutionary adaptations and bioengineering of light‐harvesting complexes

open access: yesFEBS Letters, EarlyView.
Phototrophs evolved light‐harvesting systems adapted for efficient photon capture in habitats enriched in far‐red radiation. A subset of eukaryotic pigment‐binding proteins can absorb far‐red photons via low‐energy chlorophyll states known as red forms.
Antonello Amelii   +8 more
wiley   +1 more source

Ensemble Machine Learning of Gradient Boosting (XGBoost, LightGBM, CatBoost) and Attention-Based CNN-LSTM for Harmful Algal Blooms Forecasting

open access: yesToxins, 2023
Harmful algal blooms (HABs) are a serious threat to ecosystems and human health. The accurate prediction of HABs is crucial for their proactive preparation and management. While mechanism-based numerical modeling, such as the Environmental Fluid Dynamics
Jung Min Ahn   +2 more
doaj   +1 more source

Water Quality Prediction in the Luan River Based on 1-DRCNN and BiGRU Hybrid Neural Network Model

open access: yesWater, 2021
The current global water environment has been seriously damaged. The prediction of water quality parameters can provide effective reference materials for future water conditions and water quality improvement.
Jianzhuo Yan   +3 more
semanticscholar   +1 more source

Rad27/FEN1 prevents accumulation of Okazaki fragments and ribosomal DNA copy number changes

open access: yesFEBS Letters, EarlyView.
The budding yeast Rad27 is a structure‐specific endonuclease. Here, the authors reveal that Rad27 is crucial for maintaining the stability of the ribosomal RNA gene (rDNA) region. Rad27 deficiency leads to the accumulation of Okazaki fragments and changes in rDNA copy number.
Tsugumi Yamaji   +3 more
wiley   +1 more source

Water Quality Project Evaluation A Handbook for Objectives-Based Evaluation of Water Quality Projects [PDF]

open access: yes, 1998
PDF pages ...
Bonar Bouton, Elysabeth K.   +4 more
core  

Mitochondrial fatty acid oxidation is stimulated by red light irradiation

open access: yesFEBS Letters, EarlyView.
Light at different wavelengths has distinct effects on keratinocyte viability and metabolism. UVA light abrogates metabolic fluxes. Blue and green light have no effect on metabolic fluxes, while red light enhanced oxidative phosphorylation by promoting fatty acid oxidation. Keratinocytes are the primary constituents of sunlight‐exposed epidermis.
Manuel Alejandro Herrera   +4 more
wiley   +1 more source

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