Results 91 to 100 of about 425,315 (313)

Effectiveness of Water Quality Index for Monitoring Malaysian River Water Quality

open access: yesPolish Journal of Environmental Studies, 2016
The Skudai River has experienced a general decline in water quality over the last several years due to agricultural practices, economic development, and other human activities in the river catchment. The spatial trend of water quality index (WQI) and its sub-indexes are important for determining the locations of major pollutant sources that contribute ...
Naubi, Irena   +4 more
openaire   +2 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Land use from water quality: development of a water quality index across Pennsylvania streams

open access: yesEcosphere, 2019
Anthropogenic stressors to lotic environments are diverse and often act in complex and synergistic ways through space and time. The need to adequately quantify and communicate these stressors in lotic environments is important for assessing stream health
Timothy A. Wertz, Matthew K. Shank
doaj   +1 more source

Indices of water quality and metal pollution of Nile River, Egypt

open access: yesEgyptian Journal of Aquatic Research, 2017
Nile River is the valued natural and exclusive source of fresh water in Egypt, where the drinking water supply is limited to the river. The water quality of 24 sites between Aswan and Cairo along the Nile was investigated.
Amaal M. Abdel-Satar   +2 more
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Evaluation of the quality of boreholes water using indicators like Water Quality Index (WQI), and the Comprehensive Pollution Index (CPI) [PDF]

open access: yesمجلة جامعة النجاح للأبحاث العلوم الطبيعية
Mauritania is a country with a water deficit. The majority of these regions are supplied by groundwater through boreholes. Among these regions there is the Wilaya of Akjoujt.
Soughra Dah Soueilem   +10 more
doaj   +1 more source

Designing Efficient and Sustainable Predictions of Water Quality Indexes at the Regional Scale Using Machine Learning Algorithms [PDF]

open access: gold, 2022
A. Derdour   +4 more
openalex   +1 more source

Application of Water Quality Index (WQI) For Ground Water Quality Interpretation

open access: yesInternational Journal of Innovative Technology and Exploring Engineering, 2019
Water Quality Index (WQI) is a widely used technique in defining the quality of groundwater and finding whether it is advisable for human use. It is utmost necessary steps to understand the physical and chemical parameters defining the water quality for particular period and location using WQI calculation as it gives information in a single value.
Mrs. Jeyalakshmi* Suresh Kumar   +2 more
openaire   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

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