Results 111 to 120 of about 486,083 (311)

Application of Water Quality Index for the assessment of water quality of lakes

The specific physio-chemical and biological characteristics of water determine its suitability for various purposes, including domestic, agricultural and industrial use, highlighting the importance of complete chemical analysis. An attempt is made to understand the water quality of selected lakes in and around Bangalore.
Amritha Thankachan, Dr. M. Inayathulla
openaire   +1 more source

The Application of a Water Quality Index to River Management

Water Science and Technology, 1988
River water quality in the United Kingdom is categorised within a five class system developed in 1978 (NWC). This system suffers from problems of subjectivity, reproducibility and sensitivity which limit its value in identifying benefits of management practice.
J.M. Tyson, M.A. House
openaire   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Relationship between Biological and Qualitative Indices in Surface Waters Receiving the Effluent of Fish Farms in the Northwest of Iran

Journal of Arthropod-Borne Diseases
Background: Water quality is usually measured using various indicators based on physical, chemical and biological parameters. By using the biological index that is based on the identification of the arthropod families, it is possible to make a logical ...
Farhad Pourfaraj, Malek Abazari, Eslam Moradiasl, S. Amad Mokhtariai   +3 more
doaj   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Spatial and Temporal Variations in Water Quality and Land Use in a Semi-Arid Catchment in Bolivia [PDF]

, 2019
Increasing pressures caused by human activities pose a major threat to water availability and quality worldwide. Water resources have been declining in many catchments during recent decades.
Ana Maria Romero, Ingrid Wesström, Ingmar Messing, Benjamin Gossweiler, Abraham Joel   +4 more
core   +1 more source

Indices of water quality and metal pollution of Nile River, Egypt

Egyptian Journal of Aquatic Research, 2017
Nile River is the valued natural and exclusive source of fresh water in Egypt, where the drinking water supply is limited to the river. The water quality of 24 sites between Aswan and Cairo along the Nile was investigated.
Amaal M. Abdel-Satar, Mohamed H. Ali, Mohamed E. Goher   +2 more
doaj   +1 more source

WATER QUALITY INDEX IN AN URBAN WATERSHED [PDF]

International Journal of Sustainable Development and Planning, 2016
Raissa C. Gomes, Regina M. Longo, Fernando H.S. Ribeiro, Sueli do C. Bettine, Antonio C. Demanboro, Admilson I. Ribeiro   +5 more
openaire   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source