Results 111 to 120 of about 1,680,919 (308)

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Zooplankton from Can Giuoc River in Southern Vietnam [PDF]

, 2016
In this study, the variables of zooplankton and water quality were investigated in the Can Giuoc River, Southern Vietnam. Zooplankton was monitored in April and September 2015 at 5 sampling sites in the river.
Duc, Pham Anh, Linh, Nguyen Thi Mai, Thanh, Dang My   +2 more
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Application of Water Quality Index (WQI) For Ground Water Quality Interpretation

International Journal of Innovative Technology and Exploring Engineering, 2019
Water Quality Index (WQI) is a widely used technique in defining the quality of groundwater and finding whether it is advisable for human use. It is utmost necessary steps to understand the physical and chemical parameters defining the water quality for particular period and location using WQI calculation as it gives information in a single value.
Mrs. Jeyalakshmi* Suresh Kumar, Dr. Natesan Manoharan, Dr. Rajangam Udayakumar   +2 more
openaire   +1 more source

Indices of water quality and metal pollution of Nile River, Egypt

Egyptian Journal of Aquatic Research, 2017
Nile River is the valued natural and exclusive source of fresh water in Egypt, where the drinking water supply is limited to the river. The water quality of 24 sites between Aswan and Cairo along the Nile was investigated.
Amaal M. Abdel-Satar, Mohamed H. Ali, Mohamed E. Goher   +2 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Water Quality Index of Arkavathi River and Surrounding Groundwater

International Journal of Environmental Health Engineering
Aim: Finding out the water quality of Arkavathi river, a tributary of the Kaveri system and surrounding groundwater is the aim of the present work using the water quality index (WQI) method.
M Bharath, K Arun Kumar, Syed Ariff
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Land use from water quality: development of a water quality index across Pennsylvania streams

Ecosphere, 2019
Anthropogenic stressors to lotic environments are diverse and often act in complex and synergistic ways through space and time. The need to adequately quantify and communicate these stressors in lotic environments is important for assessing stream health
Timothy A. Wertz, Matthew K. Shank
doaj   +1 more source

Building forecast maps of water quaůity for main rivers and canals in Tien Giang province, Vietnam [PDF]

, 2015
This study aims to enhance the mapping of forecast for water quality assessment in Mekong Delta provinces. The data from 32 sites from main rivers and canals in an area of around 2,482 km2 in Tien Giang Province, Vietnam, were used for calculation and ...
Duc, Pham Anh, Dung, Dang Quoc, Duong, Truong Thi Thuy   +2 more
core